The Combative and Difficult Patient


Key Concepts

  • The emergency department (ED) should develop a written plan of action to deal with violence that integrates the roles and activities of ED staff, hospital administration, security, and local authorities.

  • ED staff should be trained to recognize potentially violent individuals and to intervene with verbal de-escalation techniques prior to the use of physical or chemical restraint when possible.

  • The emergency clinician should be familiar with the use of physical and chemical restraints as well as the breadth of options for chemical sedation and circumstances that may guide selection of particular medications.

  • For the undifferentiated, severely agitated patient requiring rapid tranquilization, we recommend a benzodiazepine (such as lorazepam) either alone or with a first-generation antipsychotic (such as haloperidol).

  • The possibility of an organic (medical) cause of aggressive behavior should be considered in all violent patients, even those with known psychiatric disease.

  • Difficult patient encounters may result in undesirable implications for both patients and their ED caregivers, including compromised patient care, compassion fatigue, or professional burnout.

  • Management of the difficult patient can be optimized by understanding the multiple issues contributing to the impaired clinician-patient relationship, including factors of the ED setting (such as time constraints and lack of privacy), individual clinician influences (such as personal bias or poor communication), and patient contributions to the interaction, including behavioral, social, or substance use issues.

  • Pejorative stereotypes of difficult patients should be avoided. To aid in clinician strategies for challenging encounters, instead aim to characterize the patient’s primary difficult behaviors.

  • Understanding one’s own biases and reactions and optimizing communication are helpful strategies in dealing with a suboptimal clinician-patient relationship.

The Combative Patient

Foundations

Combative patients are among the most difficult patients encountered by emergency clinicians. Often brought in against their will, they can be agitated, confrontational, difficult to examine, and they may physically harm themselves or others. The emergency clinician should seek to control the patient and the situation, diagnose and treat reversible causes of violence, ensure that there is not an organic cause contributing to the behavior, and protect the patient, staff, and other patients from harm.

The emergency department (ED) is a volatile environment owing to high stress, illness, prolonged waiting times, and often perceived gaps in communication. Given that the ED is open 24 hours a day, 7 days a week, combined with the availability of potential hostages and accessibility to drugs or weapons, compound the potential for violent behavior. The assault-injury rate of health care occupations is nearly 10 times that of the general sector, and over half of all health care providers will be victims of violence of some form during their careers.

Emergency care providers throughout the world are more likely than other health care providers to experience violent events, such as verbal threats, physical assaults, or confrontations outside the workplace. In 2018, The American College of Emergency Physicians (ACEP) conducted a poll of 3539 emergency physicians across the country in which nearly 50% reported having been assaulted while at work in the ED, with over 70% having witnessed an assault in the workplace. In this survey, nearly all assaults were committed by the patient (97%), but in 28%, it was reported that family or friends acted as an accessory. Similar rates of violence and aggression toward physician and nursing staff are typically observed, and both men and women generally appear to be at comparable risk. , Violent incidents are far more likely to be verbal threats or acts of intimidation than physical assaults and, in the ED, may be acted out by patients, as well as their family, friends, or other visitors. The actions of combative patients have consequences that extend beyond the physical injury of ED caregivers, such as provider posttraumatic stress disorder symptoms or lost provider work productivity, and also serve as a major contributor to burnout. ,

Clinical Presentation

Patient Characteristics

The pathogenesis of violent behavior is multifactorial, with potential contributing factors including environmental, historical, interpersonal, biochemical, genetic, hormonal, neurotransmitter, or substance abuse disorders. Psychiatric illness is also a risk factor, with schizophrenia, personality disorders, mania, or psychotic depression most frequently associated with violence. Delusional schizophrenic patients may become violent, believing that others are attempting to harm them. They may also have auditory hallucinations commanding harm to others. The patient with acute mania is unpredictably dangerous because of emotional lability, a situation in which pleasantness can quickly turn to aggression. Substance abuse disorders and drug-seeking behavior are consistently associated with violent behavior in both psychiatric and nonpsychiatric populations.

Biologically, the serotonin system largely controls aggression and inhibition, with a role of diminished serotonergic function in disinhibiting aggression against self and others. Generalized brain dysfunction may predispose patients to violence by disruption of the regulation of aggression, particularly in the prefrontal or temporal cortex. Cerebral imaging documents both functional and structural impairments in violent criminals and antisocial patients.

Violent behavior also occurs in association with head trauma, hypoxia, hypoglycemia, electrolyte imbalance, infections (particularly herpes encephalitis), drug intoxication or withdrawal or adverse reaction, or metabolic and endocrine derangements. Uncommon organic causes include seizures (e.g., temporal lobe), tumors (particularly those in the limbic system), limbic encephalitis, multiple sclerosis, porphyria, Wilson disease, Huntington disease, sleep disorders, hyperparathyroidism, or vitamin and mineral deficiencies (e.g., folate, vitamin B 12 , niacin B 2 , and pyridoxine vitamin B 6 ). Although drug or ethanol intoxication and withdrawal are the most common diagnoses in combative ED patients, the mnemonic FIND ME ( f unctional [i.e., psychiatric], i nfectious, n eurologic, d rugs, m etabolic, e ndocrine) helps in broadly categorizing many important causes of violence ( Box 185.1 ).

BOX 185.1
Selected Conditions Associated With Violence

Psychiatric

  • Schizophrenia

  • Paranoid ideation

  • Catatonic excitement

  • Mania

  • Personality disorders

    • Borderline

    • Antisocial

    • Delusional depression

    • Posttraumatic stress disorder

    • Decompensating obsessive-compulsive disorders

Situational Frustration

  • Mutual hostility

  • Miscommunication

  • Fear of dependence or rejection

  • Fear of illness

  • Guilt about disease process

Antisocial Behavior

  • Violence with no associated medical or psychiatric explanation (these patients may be managed by the police or security)

Organic

Diseases

  • Delirium

  • Dementia

  • Trauma

  • Central nervous system infection

  • Seizure

  • Neoplasm

  • Cerebrovascular accident

  • Vascular malformation

  • Hypoglycemia

  • Hypoxia

  • Acquired immunodeficiency syndrome (AIDS)

  • Electrolyte abnormality

  • Hypothermia or hyperthermia

  • Anemia

  • Vitamin deficiency or toxicity (e.g., hypervitaminosis D)

  • Endocrine disorder

Drugs

  • Unanticipated reaction to prescribed medication (especially sedatives in brain-injured or elderly patients)

  • Alcohol (intoxication and withdrawal)

  • Amphetamines

  • Cocaine

  • Sedative-hypnotics (intoxication or withdrawal)

  • Phencyclidine (PCP)

  • Lysergic acid diethylamide (LSD)

  • Anticholinergics

  • Aromatic hydrocarbons (e.g., glue, paint, gasoline)

  • Steroids Synthetic cannabinoidsSynthetic cathinones

Identification of potentially violent patients is more difficult; male gender, prior history of violence, and drug or ethanol abuse have historically been positive predictors, whereas ethnicity, diagnosis, age, marital status, and education have been unreliable identifiers. Overall, the most accurate tools for predicting acute violent behavior likely rely largely on current behavioral patterns and clinical observations in the context of prior patterns of violence of the patient when known or previously documented.

Emergency Department Influences

An annual ED census over 50,000 patients, an average waiting time over 2 hours, and ED crowding are associated with an increased incidence of violence. The risk of workplace assault in the ED, however, exists across hospitals of all sizes and reflects the rate of violence in the community. Despite these risks, health care providers have not been routinely trained in the identification and management of combative patients.

Patients armed with lethal weapons pose a serious threat to staff and the potential risk posed by concealed weapons exists in all settings including pediatric EDs. In areas where community violence is prevalent, conflict may spill over into the ED when those involved in violent altercations are being treated for their injuries. The carriage of weapons in the ED population has previously been estimated at approximately 4% to 8%, with up to 27% of major trauma patients; however, not all EDs screen for weapons or use metal detectors. Unfortunately, prediction of weapons carriage in any particular patient is challenging, and it is therefore prudent to assume that all violent patients are armed until it is proved otherwise, especially those presenting with major trauma.

The deleterious effects of violence in the ED can be minimized by employing certain preventive measures and by training staff in techniques to de-escalate and limit violent behavior when it occurs ( Box 185.2 ).

BOX 185.2
Emergency Department Preparedness and Prevention of Violence
ED, Emergency department.

General Emergency Department Preparedness Considerations

Physical and system factors to minimize ED violence risk:

  • 1.

    Prominently displayed warning signs prohibiting weapons and alerting all entering that they may be screened for weapons

  • 2.

    Nondiscriminatory inquiry about weapon carriage and searches of individuals for weapons with clear local policies for staff about searches and contraband disposal

  • 3.

    A panic or alarm system to activate hospital security or local police response

  • 4.

    ED placement of dedicated telephone(s) with a direct line to police or security to request additional personnel if needed

  • 5.

    Control flow into the ED by limiting access to one or two entrances and consider buzzer access systems, and protective bulletproof glass or metal bar barriers at front desks

  • 6.

    A secure examination room with solid ceiling, shatterproof ceiling lights, heavy indestructible chairs, well-secured restraint bed, two outward swinging doors that can be locked from the outside, an emergency distress button that can be activated unobtrusively, and consideration of a video monitoring system

Primary Prevention

Control factors encouraging the development of frustration and aggression:

  • 1.

    Minimize waiting times to the extent feasible

  • 2.

    Optimize waiting room environment

  • 3.

    The presence of visible surveillance cameras

  • 4.

    The presence of a trained visible security force reflecting both hospital needs and anticipated violence based on local community prevalence

Secondary Prevention

Response to pre-violent agitation and aggression:

  • 1.

    Recognition of risk (pre-violent patients and their companions)

  • 2.

    Implementation of de-escalation techniques

  • 3.

    Minimize treatment delays of pre-violent individuals

  • 4.

    Ongoing staff training in violent management techniques to increase caregiver confidence and comfort while decreasing the rate of aggressive incidents

Tertiary Prevention

Limitation of the actual act of violence once it has occurred:

  • 1.

    Use of physical and chemical restraints

  • 2.

    Appropriate security and police intervention

  • 3.

    Apply familiar protocols for dealing with the violent individual

Initial Patient Evaluation

Evaluation of the combative patient begins with attention to safety measures. All patients should be screened for weapons before the interview. The use of metal detection is ideal upon ED entry, and additional attention may be needed for patients brought to the ED by ambulance and thereby bypassing routine security screens. The practice of undressing patients and placing them in a gown is useful as a non-confrontational survey for potential weapons that also discourages fleeing in some circumstances or, conversely, aids in identification if a violent patient suddenly flees from the ED.

The ideal setting for the patient interview emphasizes privacy without isolation, such as a seclusion room specifically designed for the interview of potentially dangerous patients. Prior to the medical interview, security should be stationed strategically and the door left open to facilitate both intervention and escape for the provider. The patient and interviewer may be seated roughly equidistant from the door, or the interviewer may sit between the patient and the door. Blocking of the door, however, poses a risk of harm to the clinician if the patient feels the urge to escape. Ideally, examination room doors should swing out, and more than one exit should be available. The clinician should have unrestricted access to the door and avoid sitting behind a desk. The room should not contain heavy or potentially dangerous objects that may be thrown. There ideally should be a mechanism to alert others of danger, such as a panic button or a code word or phrase that summons security (e.g., “I need ‘Dr. Armstrong’ in here.”). For personal protection of the provider, earrings, necklaces, and neckties should be removed. Personal accessories that may be used against the caregiver, such as a stethoscope or scissors, should also be removed. The clinician should be aware of any objects within the room or on the patient’s body that might be used as weapons, such as pens, watches, necklaces, key chains, cell phones, or belts.

Violence risk assessment of a potentially combative patient can be difficult. Violence often erupts after a period of mounting tension. The astute practitioner may identify verbal or nonverbal cues and may subsequently have the opportunity to defuse the situation. In a typical scenario, the patient first becomes angry, then resists authority, and finally becomes confrontational and violent. When clinicians have a “gut feeling” that a dangerous situation may be developing, they should take appropriate precautions. Violent behavior may also erupt without warning, especially in patients with an organic brain syndrome, so clinicians should not feel overly confident in their ability to sense impending danger. An obviously angry ED patient should be considered potentially violent. Patients with a history of violent behavior are more likely to inflict serious injury, and certain patient behaviors may suggest impending violence ( Box 185.3 ).

BOX 185.3
Patient Behaviors Suggesting Impending Violence

  • Provocative behavior

  • Angry demeanor

  • Loud, aggressive speech

  • Tense posturing (e.g., gripping arm rails tightly, clenching fists)

  • Pacing or frequently changing body position

  • Aggressive acts (e.g., pounding walls, throwing objects, hitting oneself)

To prevent escalation, the patient should be removed from contact with other agitated accomplices, as well as from other provocative patients. A quiet area enabling direct observation is optimal. Because increased waiting times correlate positively with violent behavior, consider evaluating the potentially violent patient accelerated to prevent escalation of aggression. When feasible, expeditious triage and evaluation of these patients may avoid the challenging consequences of violence for the patient at hand, the ED staff, and ultimately the care of other ED patients. Often, the perception of preferential treatment alone may serve to defuse the patient’s anger.

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