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D efinition — An early form of clear-cell neoplasia with malignant cytology and the absence of invasion. Clinical Features Epidemiology Clear-cell tumors of this type typically present as adenofibromas that can arise de novo or from within endometriotic cysts. Uncommon…

D efinition — A malignant, endometriosis-associated epithelial tumor. Clinical Features Epidemiology Uncommon. Distinct gene expression profile. Present in postmenopausal women with a mean age in the 50s. You’re Reading a Preview Become a Clinical Tree membership for Full access and…

D efinition — An invasive ovarian carcinoma with a transitional growth pattern that contains areas of benign or borderline Brenner tumor. Clinical Features Epidemiology Rare. Can present at a range of ages, but the mean age is in the 60s.…

D efinition — A benign ovarian tumor composed of cells resembling transitional epithelium of the urinary tract. Clinical Features Epidemiology Uncommon but seen periodically in practice. Brenner tumors may represent up to 5% of benign epithelial tumors of the ovary.…

D efinition —A morphologic spectrum of tumors arising in endometriosis and displaying a müllerian (rather than intestinal) phenotype. Clinical Features Epidemiology Rare, reports limited to small series. Associated with borderline neoplasia usually serous or mucinous. Most present in the fourth…

D efinition — Noninvasive epithelial and stromal tumors with an atypical endometrioid epithelial component. Clinical Features Epidemiology Uncommon but not exceedingly rare; less than 200 reported cases but most pathologists will encounter at some point in their practice. Similar to…

D efinition — A benign epithelial and stromal tumor with an endometrioid epithelial component. Clinical Features Epidemiology Rare; these lesions represent less than 1% of all benign ovarian tumors. Most common in postmenopausal patients or women in their late reproductive…

D efinition — An adenocarcinoma typically derived from endometriosis and displaying well to moderate differentiation. Clinical Features Epidemiology Approximately 40% of low-stage tumors are associated with endometriosis. Those with endometriosis tend to be younger than those without. Approximately 5% associated…

D efinition — Marked intramucosal atypia in a borderline mucinous tumor of the ovary. Clinical Features Epidemiology The second most common epithelial tumor of the ovary and 12% to 15% of ovarian tumors. Approximately 10% of mucinous tumors are borderline.…

D efinition — An atypical proliferative mucinous tumor with intestinal differentiation, without stromal invasion or intraepithelial carcinoma. Clinical Features Epidemiology The second most common epithelial tumor of the ovary and 12% to 15% of ovarian tumors. Approximately 10% of mucinous…