Uses RX for hypothyroidism. In USA, 7.5% of pregnant women plus an additional 500,000 people per y develop hyperthyroidism. Rx for goiter associated with hyperthyroidism; second drug to methimazole due to greater side effects with PTU except in pregnancy (methimazole…
Uses Incidence in USA: 3600 per y Rx for preop pheochromocytoma; occasionally for chronic Rx of pheochromocytoma and sympathetic hyperactivity states, carcinoid syndrome, BPH Perioperative Risks Drug interactions: Sometimes requires very high doses of α-adrenergic agents to produce vasoconstriction. Vasodilation,…
Risk Incidence in USA is 3–15% of the whole population (increased fourfold in last 15 y, presumably due to increase in obesity). M:F ratio: 2.5:1. Race with highest prevalence: Unknown. Perioperative Risks Increased risk of pulm Htn, RV failure, and…
Risk Incidence USA is 3–12% of middle-aged adults (which has increased fourfold in last 15 y, presumably due to increase in obesity). The M:F ratio is 2–2.5:1; obstructive or mixed. Risk increases with male sex, upper middle age (55–64 y),…
Risk Incidence in USA: 3 million; 350 million in world Race with highest prevalence: African Americans Perioperative Risks Increased risk of complications following CABG. Periop mortality rate in published cases of SA trait is 0.8%. Some increased risk of CVA…
Risk Incidence in USA: 0.03–0.04% (∼80,000) by autopsy of nonselected individuals. Prevalence: 0.1–0.3% of individuals with sustained Htn have pheochromocytoma. At least 20% are now diagnosed when the tumor is incidentally found during abdominal MRI or CT for other reasons.…
Risk Incidence in USA: 1.5 million/y develop acute MI; about 50% are silent (without enough symptoms to cause a medical visit); decreased rate of death in the United States balanced by increased population has kept MI numbers constant since 1970…
Risk Incidence in USA: 300,000-500,000 individuals/y develop hyperthyroidism. In addition, 7.5% of pregnant women become hyperthyroid (highest prevalence in second trimester). 1:1000 females; 1:3000 males. Race with highest prevalence: Unknown. Perioperative Risks Risk related to occurrence of thyroid storm; increased…
Key Points ▪ The history and physical examination most accurately predict the risks of anesthesia and the likelihood of required changes in monitoring or therapy. ▪ For diabetic patients, end-organ dysfunction and the degree of glucose control in the perioperative…
Risk Incidence in USA: 1.25 million. Perioperative Risks Risk of requiring a CABG is increased 5–10 times in presence of ESRD, CHF, or autonomic neuropathy; without these conditions, the risk is 1-1½ times that of a normal person. Worry About…