Tag Michael D. Tharp

Mastocytosis

Key features ▪ Mastocytosis can develop from birth to adulthood and may involve only the skin (most children and some adults) or multiple organs such as the bone marrow, liver, spleen, and/or lymph nodes (primarily adults) ▪ Childhood disease is…

Mast Cell Disease

Key Points Mastocytosis is a disease of both children and adults. Most children have skin-limited disease and an excellent prognosis. Many adults have either cutaneous only or indolent systemic mastocytosis, and a very good prognosis. Patients with more advanced disease…

Antihistamines

Questions Q32.1 How do first- and second-generation antihistamines differ regarding lipophilic properties and anticholinergic effects, and what are the resultant clinical differences? (Pgs. 350, 352) Q32.2 What are the advantages of second-generation over first-generation H 1 antihistamines? (Pgs. 350, 352)…