Acknowledgments Dr. Sempoux extends very special thanks to Professor Darius Moradpour and Dr. Sabine Schmidt-Kobbe (CHUV, Lausanne, Switzerland) for their critical clinical advice in formulating this chapter. The term cirrhosis is derived from the Greek word “kirrhos” meaning “yellow” or…
Abbreviations CPA collagen proportionate area ECM extracellular matrix HRC hepatic repair complex HSC hepatic stellate cell MF myofibroblast MMP matrix metalloproteinase SMA smooth muscle actin TIMP tissue inhibitor of metalloproteinase Regression of fibrosis is no longer a mythical concept. First…
Abbreviations ALT alanine aminotransferase AST aspartate aminotransferase AUC area under the curve CPA collagen proportionate area HAI histologic activity index HCV hepatitis C virus MIA morphometric image analysis The concepts of grading and staging have been borrowed from the world…