Medical treatment of patients with peripheral artery disease (PAD) is targeted at preventing adverse cardiovascular and limb outcomes and improving limb function. Atherothrombotic complications such as myocardial infarction (MI), ischemic stroke, and cardiovascular death are referred to as major adverse…
Overview Drugs for Patients With Peripheral Artery Disease Peripheral artery disease (PAD) is broadly defined as arterial occlusive disease outside of the coronary circulation and generally refers to atherosclerotic occlusive disease. While nonatherosclerotic occlusive disease including that related to fibromuscular…
Introduction Myocardial infarction (MI) is caused by atherothrombosis (see Chapter 3 ), with platelets playing a pivotal role in the initial onset of MI and its recurrence. Antiplatelet therapy targets this key element in the pathobiology of cardiovascular ischemic events.…
Acknowledgment The authors thank Dr. Peter Libby, co-author of this chapter in editions 6 to 10, for his contributions and mentorship. Additional content is available online at Elsevier eBooks for Practicing Clinicians Peripheral artery disease (PAD) generally refers to acute…
Additional content is available online at Elsevier eBooks for Practicing Clinicians Acute chest pain remains one of the most common reasons for seeking care in the emergency department (ED), accounting for almost 10% of the approximately 100 million nontraumatic visits…