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Abbreviations AIH autoimmune hepatitis AIH-PBC autoimmune hepatitis–primary biliary cholangitis AIH-PSC autoimmune hepatitis–primary sclerosing cholangitis ALT alanine aminotransferase ANA antinuclear antibodies AST serum asparate ASMA antismooth muscle antibodies GGT gamma-glutamyl transpeptidase HLA human leukocyte antigen IgG immunoglobulin G LKM1 liver-kidney microsomal…
Liver Transplantation Liver transplantation is performed in patients with liver failure caused by acute or chronic liver disease, selected hepatic tumors, and some metabolic diseases. Approximately 7000 liver transplants (LT) are performed annually in the United States. The graft survival…
Major Histologic Patterns of Injury Because the liver presents with a relatively small repertoire of responses to injury, there is significant histologic overlap among liver diseases, making specific diagnosis challenging. A pattern-based approach enables the pathologist to generate a relatively…