■ Introduction The aorta is the largest artery in the body, arising from the left ventricular outflow tract and branching throughout the body. The spectrum of thoracic aortic disease is wide, with causes that may be chronic or acute, congenital…
Introduction Interstitial lung disease (ILD) refers to a broad category of diffuse parenchymal lung diseases characterized by inflammation and/or fibrosis of the lungs. Patients invariably present with dyspnea of varying time course and severity. Patients are often hypoxemic, and pulmonary…
Abnormalities of Diaphragmatic Motion: Diaphragmatic Paralysis, Weakness, and Eventration Etiology, Prevalence, and Epidemiology The diaphragm is the primary muscle of ventilation, and dysfunction of the diaphragm is an underrecognized cause of dyspnea. Dysfunction of the diaphragm can be classified as…
Etiology The number of drugs recognized to cause an adverse pulmonary reaction of one kind or another is reported to be more than 600 and continues to rise yearly with the advent of new medications. Pharmacologic groups associated with pulmonary…
Bronchiolitis refers to a wide variety of inflammatory and fibrotic disease processes affecting the small airways. Bronchiolitis is common and may be the primary manifestation in various clinical settings (e.g., infections, connective tissue diseases (CTDs), inhalational injuries, cigarette smoking, drug…
Asthma is an inflammatory disease characterized by increased airway reactivity and by airflow obstruction that is at least partially reversible and results in recurrent episodes of wheezing, breathlessness, and cough. Etiology Asthma can be divided into two main categories: extrinsic…
Etiology Pulmonary edema is defined as an abnormal accumulation of fluid in the extravascular compartments (interstitial and airspace) of the lung. Traditionally, pulmonary edema has been divided into hydrostatic edema and permeability edema based on the presumed mechanism. Hydrostatic edema…
Fat Embolism Etiology, Prevalence, and Epidemiology The term fat embolism refers to the presence of globules of free fat within the pulmonary vasculature. Fat embolism is common among trauma patients, especially those with long bone or pelvic fractures. In the…
Etiology, Prevalence, and Epidemiology Takayasu arteritis, also known as pulseless disease or Martorell syndrome, is an idiopathic chronic granulomatous arteritis affecting medium and large arteries with a predilection for the aorta and its main branches. It is seen most commonly…
Etiology, Prevalence, and Epidemiology Behçet disease is an uncommon systemic disorder of unknown etiology characterized by vasculitis and the triad of recurrent ulcers of the oral and genital mucosa with relapsing uveitis. Vascular complications develop in 20% to 40% of…