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Key Points Psoriasis is common, affecting over 125 million worldwide. Comorbidities include diabetes, hypertension, dyslipidemia, obesity, myocardial infarction, stroke, cardiovascular death, lymphoma, autoimmune disorders, and renal disease. TNF signaling and the IL-23/Th17 pathways are critical in the pathogenesis of psoriasis,…
Questions Q29.1 What are the two subunits that make up interleukin (IL)-23? (Pg. 321) Q29.2 What subunit of IL-23 do IL-23 inhibitors target? (Pg. 321) Q29.3 What interleukin inhibitors are directed against IL-23? (Pg. 321) Q29.4 How does the efficacy…