Tag Eric A. Walker

Hypertrophic Osteoarthropathy

Etiology Hypertrophic osteoarthropathy (Pierre Marie–Bamberger syndrome) is characterized by digital clubbing and periosteal proliferation along the long tubular bones. It can be classified as either primary (idiopathic/hereditary) or secondary hypertrophic osteoarthropathy. The primary form of the disease, also known as…

Amyloidosis

Etiology Amyloidosis comprises a heterogeneous group of diseases in which otherwise normal proteins acquire alternative misfolded states and form insoluble fibrils termed amyloid fibrils. Subsequently, extracellular deposition of amyloid fibrils into various organs and tissues results in infiltration, swelling, and…