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Liver Transplantation Liver transplantation is performed in patients with liver failure caused by acute or chronic liver disease, selected hepatic tumors, and some metabolic diseases. Approximately 7000 liver transplants (LT) are performed annually in the United States. The graft survival…

Primary hepatocellular neoplasms are much less common than metastatic tumors to the liver. The former may arise from either the epithelial or mesenchymal component of the hepatic parenchyma and rarely may also show both lines of differentiation. Hepatocellular neoplasms may…

Major Histologic Patterns of Injury Because the liver presents with a relatively small repertoire of responses to injury, there is significant histologic overlap among liver diseases, making specific diagnosis challenging. A pattern-based approach enables the pathologist to generate a relatively…