D efinition — Diffuse or multifocal fibrin deposition that fills and obliterates the intervillous space along a significant portion of the chorionic plate. Clinical Features Epidemiology Uncommon (less than 1% of placentas). Occasionally associated with abnormal maternal clotting (APhA, ATIII…
D efinition — Detached strips of amniotic membrane that restrict fetal growth, resulting in asymmetric anomalies that do not follow a recognized developmental pattern. Clinical Features Epidemiology One in 2,500 to 10,000 deliveries. You’re Reading a Preview Become a Clinical…
PITFALL D efinition — Thrombus formation within the umbilical cord, within its tributaries on the placental surface, or within stem villi. Clinical Features Epidemiology Common; seen in 3% to 10% of placentas. Increased incidence with maternal diabetes. You’re Reading a…
D efinition — Umbilical cord with two vessels; one umbilical artery and one vein. Clinical Features Epidemiology Common; noted in 1% to 3% of all gestations. More frequent in spontaneous abortions. More frequent in white women than black or Asian…
D efinition — True knots in the umbilical cord. Clinical Features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
D efinition — Benign expansile nodule of capillaries and stromal cells. Clinical Features Epidemiology Uncommon; this finding is seen in less than 0.5% of placentas. Associated with twin gestations and preeclampsia. You’re Reading a Preview Become a Clinical Tree membership…
D efinition — A subset of extravillous trophoblastic tumor that is thought to arise from an extravillous (transitional) trophoblast that forms a transition from villous cytotrophoblast to mature extravillous trophoblast. These cells are found in the chorionic membrane, maternal surface…
D efinition — An abnormal early implantation site (IS) that can be identified in the setting of a molar pregnancy. Clinical Features Epidemiology Atypical molar ISs may be seen in the setting of any molar pregnancy. They are much more…
PITFALL D efinition —A malignancy that arises from the early implantation site extravillous trophoblasts. Clinical Features Epidemiology Placental site trophoblastic tumors (PSTT) are rare and were only recognized as a malignancy in 1981. PSTT are most commonly seen following a…
PITFALL D efinition — Choriocarcinoma occurring concurrently with a normal pregnancy. Clinical Features Epidemiology Intraplacental choriocarcinoma is exceedingly rare. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are…