D efinition — A rare variant of invasive adenocarcinoma originating in the endocervix. Clinical Features Epidemiology Limited to case reports. Wide age range, but most present in the fourth or fifth decade. Human papillomavirus (HPV) associated. May be found with…
D efinition — A carcinoma resembling an upper genital tract serous carcinoma but originating in the cervix and usually human papillomavirus (HPV) related. Clinical Features Epidemiology Rare. There is a distinctly bimodal age distribution; most patients are under age 45,…
D efinition — A deceptively bland-appearing mucinous adenocarcinoma of the cervix. Atypical lobular endocervical glandular hyperplasia (ALGH) is considered a potential precursor to minimal deviation adenocarcinoma (MDA). Clinical Features Epidemiology Uncommon. Not associated with human papillomavirus (HPV). Reproductive-age women; mean…
D efinition —A unique, typically HPV-negative adenocarcinoma that has been associated with prenatal diethylstilbestrol exposure. Clinical Features Epidemiology Rare. Historically linked to diethylstilbestrol (DES) exposure in utero. Sporadic occurrences now much more frequent than DES-related cases. Wide age range, with…
D efinition — Invasive adenocarcinoma originating in the endocervix. Clinical Features Epidemiology Average age at diagnosis is early 40s. Human papillomavirus (HPV) associated. A positive association with oral contraceptive use has been noted, but the mechanism is not understood. Not…
D efinition —A florid pattern of endocervical adenocarcinoma in situ (AIS) that mimics invasive adenocarcinoma. Clinical Features Epidemiology The same as for conventional AIS. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles…
D efinition — Early-stage invasive endocervical adenocarcinoma. Clinical Features Epidemiology Average age at diagnosis is early 40s. Human papillomavirus (HPV) associated. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If…
D efinition — A well-differentiated adenocarcinoma with a major exophytic and villoglandular component. Clinical Features Epidemiology Wide age range (third to seventh decades) with a mean age of 38 years. Human papillomavirus (HPV) associated. You’re Reading a Preview Become a…
D efinition — Changes seen in the cervical-vaginal epithelium following radiation therapy. Clinical Features Epidemiology A common finding in tissue samples following radiation therapy to the genital area. You’re Reading a Preview Become a Clinical Tree membership for Full access…
D efinition — A multinucleated endocervical cell atypia commonly associated with chronic inflammation. Clinical Features Epidemiology Relatively common, occasionally pronounced. Typically reproductive age, but can occur at any age. You’re Reading a Preview Become a Clinical Tree membership for Full…