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Simple atrophy
Definition
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Small, benign glands arranged in nests with reduced cytoplasmic volume in luminal epithelial cells. Simple atrophy maintains relatively normal glandular spacing and reduced luminal diameter.
Clinical features
Epidemiology
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Typically affects the elderly with the prevalence and extent of gland involvement increasing with age; however, it has been reported in at least 70% of men aged 19–29 years.
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Frequent finding in men on androgen deprivation therapy.
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