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Renal cell carcinoma with somatic mutations in TSC/mTORC1 genes
Definition
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A group of recently described renal cell carcinomas with morphology similar to tumors in patients with tuberous sclerosis complex (TSC) and harboring somatic mutations in the genes of the TSC and mTORC1 pathways. They may have diverse morphological patterns.
Clinical features
Epidemiology
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Incidence currently unknown but rare; many were diagnosed as “unclassified RCC” or “unclassified renal oncocytic tumors.”
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