Propantheline

General information

Propantheline is an anticholinergic drug. Oral doses are 7.5–30 mg, the latter being used at bedtime; injections of 15 mg have been used in radiology. The persisting doubt as to the incidence of adverse reactions probably reflects the poor and variable systemic availability of the oral form, which also seems to account for conflicting reports about its efficacy. All typical anticholinergic reactions can occur if effective doses are given, but central nervous and ocular reactions are relatively slight. Propantheline is not contraindicated in glaucoma or prostatic hyperplasia, but it can influence the response of these conditions to other treatment and hence should be used with some caution.

Organs and systems