Papillary renal cell carcinoma


  • A histological subtype of renal cell carcinoma (RCC) with predominant tubulopapillary architecture and characteristic genetic changes; 1.5 cm is the size threshold for papillary RCC; smaller low-grade lesions without fibromuscular pseudocapsule are classified as papillary adenoma.

Clinical features


  • Second most common RCC subtype

  • Ten to 15% of all RCCs

  • Age distribution similar to clear cell RCC

  • Male predominance (male-to-female ratio, 2:1 to 4:1)

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