Lumbar disc herniation

1 Describe the prevalence and natural history of lumbar disc herniation. contrast the prevalence and natural history of lumbar disc herniation and low back pain. The lifetime prevalence of a symptomatic lumbar disc herniation in the adult population is approximately 2%. The natural history of sciatica secondary to lumbar disc herniation is spontaneous improvement in the majority of cases. Among patients with radiculopathy secondary to lumbar…

Thoracic disc herniation and stenosis

1 Is thoracic disc herniation a common clinical problem? No. The incidence of symptomatic thoracic disc herniation has been reported as 1 per million patients. It is estimated that 0.15%–4% of all symptomatic disc protrusions occur in the thoracic spine. The lower rate of symptomatic disc herniation in the thoracic region compared with the cervical and lumbar regions is attributed to the stability provided by the…

Cervical degenerative disorders

1 Define cervical spondylosis. how does this condition present in clinical practice? Cervical spondylosis is a nonspecific term that refers to age-related degenerative changes within the cervical spinal column. The degenerative process can affect the intervertebral discs, facet joints, uncovertebral joints, and associated soft tissue supporting structures. Often patients with cervical spondylosis have little or no pain. Positive radiographic findings in asymptomatic patients have been reported…

Pathophysiology and pathoanatomy of degenerative disorders of the adult spine

1 What factors play a role in the development of degenerative disorders of the spine? The prevalence and progression of spinal column degenerative changes are associated with increasing age, but remain asymptomatic in many individuals. Mechanical, traumatic, nutritional, biochemical, and genetic factors interact and contribute to the development of spinal degeneration. The relative importance of these factors varies among individuals and remains incompletely understood. Evidence suggests…

Pediatric spinal trauma

General considerations 1 Why is it important to consider the normal growth and development of the spine when evaluating a child with a suspected spinal injury? Knowledge of the developmental anatomy of the spine is important to avoid misdiagnosis of anatomic differences such as normal physes, synchondroses, and secondary ossification centers as acute fractures. The atlas (C1) is formed from three ossification centers: the anterior arch…

Spondylolysis and spondylolisthesis in pediatric patients

Definitions 1 Define spondylolysis. Spondylolysis is a unilateral or bilateral defect in the region of the pars interarticularis that may or may not be accompanied by vertebral displacement. The origin of the term spondylolysis is from the Greek words spondylo (vertebra) and lysis (break or defect). 2 Define spondylolisthesis. Spondylolisthesis refers to anterior displacement of the cranial vertebral body in relation to the subjacent vertebral body.…

Sagittal plane deformities in pediatric patients

Background 1 Describe how sagittal plane alignment of the cervical, thoracic, and lumbar spine changes from birth to adulthood. The sagittal alignment of the spine is dynamic and changes with age. In newborns the spinal column possesses a single C-shaped sagittal curve. Cervical lordosis develops as an infant gains independent head control and lumbar lordosis develops with progression to standing and walking. Young children have positive…

Neuromuscular spinal deformities

General concepts 1 Why do patients with neuromuscular disorders develop spinal deformities? Neuromuscular spinal deformities develop in patients with underlying neuropathic or myopathic disorders due to trunk muscle weakness, spasticity, or spinal imbalance, which compromise the ability to maintain normal alignment of the spine and pelvis. Asymmetric spinal column loading of the immature spine leads to asymmetric vertebral body growth due to the Hueter-Volkmann principle, which…

Congenital spinal deformities

1 Define congenital scoliosis. A lateral curvature of the spine caused by vertebral anomalies that produce a frontal plane growth asymmetry. The anomalies are present at birth, but the curvature may take years to become clinically evident. 2 What genes are thought to be responsible for the congenital spinal malformations? Homeobox genes of the Hox class. 3 When do congenital vertebral anomalies form? During weeks 4–6…

Idiopathic scoliosis

1 What is idiopathic scoliosis? Idiopathic scoliosis is the most common type of scoliosis. At present it is uncertain whether this deformity represents a single disease entity or reflects a similar clinical expression of several different disease states. Idiopathic scoliosis is defined as a spinal deformity characterized by lateral bending and fixed rotation of the spine in the absence of a known cause. The criterion for…

Early-onset scoliosis

Background 1 Why is the age of onset of scoliosis important? Growth and development of the spinal column, thorax, and lungs are interdependent. Deformities affecting the spine and thorax in the first decade of life adversely impact lung development and function. Long-term follow-up of patients with untreated scoliosis ( ) has shown increased mortality secondary to respiratory failure and cardiovascular disease in those with infantile scoliosis…

Pediatric cervical disorders

Development of the cervical spine 1 What family of genes regulates development of the vertebral column? The Hox (homeobox) and Pax (paired box) genes regulate embryonic differentiation and segmentation of the developing vertebral column. 2 Describe the development of the atlas (C1). The atlas is formed from three primary ossification centers: the anterior arch and two neural arches. The anterior arch is not ossified at birth…

Pediatric back pain

Evaluation 1 Discuss the epidemiology of back pain in children compared with adults. Traditionally, back pain in children was considered uncommon, and thought to be associated with a definable cause. Current data show that back pain is a frequent complaint in the pediatric population and that the probability of identifying a specific cause is low. Back pain is much less common before age 10, increases during…

Spinal cord stimulation and implantable drug delivery systems

1 What is neuromodulation? Neuromodulation involves the use of both implantable and nonimplantable medical device technologies for treatment of disease through enhancement or suppression of the activity of the nervous system using electrical, pharmacologic, or other agents. Neuromodulation therapies may target the brain, spinal cord, peripheral nerves, and autonomic nervous system. Examples of neuromodulation therapies include spinal cord stimulation, deep brain stimulation, peripheral nerve stimulation, and…

Revision spine surgery

General considerations 1 Why is the term failed back surgery syndrome considered controversial? Failed back surgery syndrome is an imprecise term used to refer to patients with unsatisfactory outcomes after spine surgery due to persistent or recurrent pain in the spine and/or extremities. This term does not identify a specific diagnosis responsible for persistent symptoms and implies that additional treatment will not provide benefit. Patients with…

Artificial disc replacement

1 Discuss some limitations associated with nonarthroplasty surgical treatment options for degenerative spinal conditions. Neural decompression procedures violate the structural integrity of the spine and may lead to segmental spinal instability unless fusion is performed. Spinal fusion procedures increase stress at adjacent spinal levels and may accelerate the degenerative process leading to adjacent level degeneration, instability, facet joint degeneration, spinal stenosis, and vertebral body fracture. An…

Minimally invasive spine surgery

1 What is minimally invasive spine surgery? Minimally invasive spine (MIS) surgery is a surgical approach or technique intended to provide equivalent or superior outcomes compared with conventional open spine surgery as a result of limiting approach-related surgical morbidity. In spine surgery, as with most other invasive procedures, less is more as long as surgical goals are fully met. Principles shared by MIS procedures include: Small…

Instrumentation and fusion at the lumbosacral junction and pelvis

1 What is the lumbosacral junction? The lumbosacral junction consists of the L5 vertebra, the sacrum, and the articulations between both segments, consisting of the anteriorly located L5–S1 disc and posteriorly located L5–S1 facet joints. It also includes the ligamentous and muscular structures supporting this important motion segment. 2 Why is the lumbosacral junction important? It is the transition between the mobile lumbar spine and the…

Thoracic and lumbar spine instrumentation

General considerations 1 Summarize the functions of spinal instrumentation in thoracic and lumbar fusion procedures. Enhance fusion . Spinal implants immobilize spinal segments during the fusion process and thereby increase the rate of successful arthrodesis. Restore spinal stability . When pathologic processes (e.g., tumor, infection, fracture) compromise the integrity of the spinal column, spinal implants can restore stability. Correct spinal deformities . Spinal instrumentation can provide…

Occipital and cervical spine instrumentation

1 What are the indications for use of cervical spinal instrumentation? To immobilize an unstable spinal segment To promote bony union To improve soft tissue healing To correct spinal deformity To decrease or eliminate the need for external immobilization 2 How are the various types of cervical spinal implants classified? No universal classification exists. Cervical spinal implants may be classified descriptively by: Location of implant: anterior…