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Hypercalcaemia is a serum calcium >2.62 mmol/L (normal range 2.1–2.6 mmol/L). It may be an asymptomatic laboratory finding. Symptoms usually become apparent with levels >3.50 mmol/L.
Malignancy
Solid tumour with lytic bony metastases, e.g. Ca breast, bronchus
Solid tumours with humoral mediation, e.g. inappropriate PTH secretion with carcinoma of the bronchus, carcinoma of the kidney
Multiple myeloma
Hyperparathyroidism (primary, secondary, tertiary)
Hyperthyroidism
Drugs, e.g. thiazide diuretics, lithium
Addison’s disease
Paget’s disease of bone
Excess intake of vitamin A, vitamin D or calcium
Sarcoidosis
Familial hypocalciuric hypercalcaemia
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