Glucocorticoids


Uses

  • Used to treat a wide range of illnesses including but not limited to autoimmune disorders, postop nausea and vomiting, and chronic pain

Overview/Pharmacology

  • Adrenal cortex produces and releases two different types of corticosteroids: Mineralocorticoids (maintain salt and fluid balance) and glucocorticoids (affect metabolism and inflammation).

  • Glucocorticoids have significant, wide-ranging physiologic effects by binding to cell surface receptors and crossing cell membranes to modify genetic expression.

  • Endogenous glucocorticoids include cortisol.

  • Exogenous glucocorticoids include prednisone, prednisolone, triamcinolone, dexamethasone, and betamethasone.

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