Diethylenetriamine penta-acetic acid

General information

Diethylenetriamine penta-acetic acid (DTPA) is a chelating agent that has been used in radiolabeled form as a tracer. It has been used in the following combinations:

• DTPA: to assess iron body stores [ ];

• ¹¹¹ indium-DTPA: to label proteins, such as albumin [ ] and monoclonal antibodies [ ], for the radiodetection of cancers;

• ^99m technetium-DTPA: for scanning organs such as the kidneys [ ], lungs [ ], and brain [ ];

• dysprosium-DTPA: in experimental imaging of cerebral ischemia [ ];

• ⁹⁷ ruthenium-DTPA: to label cerebrospinal fluid [ ];

• gadolinium-DTPA: as a contrast agent in computed tomography [ ] and magnetic resonance imaging [ ].