General information

The genera in the family of Cucurbitaceae ( Table 1 ) include cucumbers, gourds, and melons.

Table 1
Genera of Cucurbitaceae
Apodanthera (apodanthera)
Benincasa (benincasa)
Brandegea (starvine)
Bryonia (bryony)
Cayaponia (melonleaf)
Citrullus (watermelon)
Coccinia (coccinia)
Ctenolepis (ctenolepis)
Cucumis (melon)
Cucumeropsis (cucumeropsis)
Cucurbita (gourd)
Cyclanthera (cyclanthera)
Doyerea (doyeria)
Ecballium (squirting cucumber)
Echinocystis (echinocystis)
Echinopepon (balsam apple)
Fevillea (fevillea)
Hodgsonia (hodgsonia)
Ibervillea (globeberry)
Lagenaria (lagenaria)
Luffa (luffa)
Marah (manroot)
Melothria (melothria)
Momordica (momordica)
Psiguria (pygmymelon)
Sechium (sechium)
Sicana (sicana)
Sicyos (burr cucumber)
Sicyosperma (sicyosperma)
Telfairia (telfairia)
Thladiantha (thladiantha)
Trichosanthes (trichosanthes)
Tumamoca (tumamoca)

Bryonia alba

Bryonia alba (white bryony) contains toxic triterpenoids called cucurbitacins, which are drastic laxatives and emetics and can cause the symptoms of food poisoning [ ].

Citrullus colocynthis

The dried pulp of the fruit of Citrullus colocynthis (colocynth) is a drastic laxative, which contains toxic cucurbitacins.

A man experienced vomiting, colicky pain, and bloody diarrhea after self-medication with C. colocynthis [ ]. Hemorrhagic colitis secondary to ingestion of colocynth has been reported [ ]. In three cases of toxic acute colitis 8–12 hours after ingestion of colocynth for ritual purposes, the prominent clinical feature was dysenteric diarrhea; colonoscopic changes included congestion and hyperemia of the mucosa with abundant exudates but no ulceration or pseudopolyp formation; there was rapid recovery within 3–6 days, with normal endoscopy at day 14 [ ].

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