Cryoablation therapy-induced changes


  • Cryosurgical ablation refers to rapid deep freezing of the prostate gland.

  • Multiple cryoprobe needles filled with circulating liquid nitrogen transform the prostate into an ice ball.

  • Cryoablation results in substantial tissue destruction and death of benign and malignant cells.

  • The flow of liquid nitrogen through the probes is adjusted to create the desired freezing pattern and extent of tissue destruction in the prostate.

  • Liquid nitrogen does not come in contact with tissue.

  • Given the focal nature of the treatment, the histologic changes are most likely to be confined to the targeted areas.

Clinical features

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