Key points Imaging plays an important role in diagnosis Thermal ablation is becoming a treatment option for select patients with small tumors techniques include radiofrequency and cryoablation long-term follow-up with imaging is necessary Embolization can be used in the treatment…
Key points Liver metastasis is a major cause of mortality and morbidity in patients with cancers of various origins and presents a therapeutic challenge because only a few patients are candidates for surgical resection, and systemic chemotherapy offers limited benefit.…
Key points Incidence and prevalence of GEP-NET is increasing. Recently approved systemic targeted therapeutic agents and local therapies have rekindled interest in NET management. Multidisciplinary centers employing a myriad of tumor therapies including strategies of image-guided techniques are poised to…
Colon cancer—an overview Colorectal cancer (CRC) is the fourth most frequently diagnosed cancer, the second leading cause of cancer-related death in the United States, and recent studies estimate that 100,000 new cases of colon cancer and 40,000 of rectal cancer…
Key points Precise assessment of disease progression and adequate selection of initial therapeutic options should be performed through a multidisciplinary approach in the treatment of liver metastases. Selected patients with colorectal liver metastases are candidates for curative hepatic resection with…
Key points The treatment of colorectal cancer, metastatic to liver, should be optimally managed within the context of a multidisciplinary team to improve patient-centered outcomes. Treatment intent should be categorized as ““curative,” “potentially curative,” “noncurative for active therapy” (the majority)…
Key points In general, the higher the cholangiocarcinoma (type 3 and type 4) and the more multifocal the disease/obstruction, the more likely the patient is to require percutaneous therapy/drainage rather than endoscopic drainage. The two chief indications for preoperative biliary…
Key points Although relatively rare, cholangiocarcinoma is the second most common primary hepatobiliary malignancy in the United States, and its incidence is increasing. Surgical treatment remains the cornerstone of curative therapy. Resection frequently requires a major procedure but can be…
Key points Cytotoxic chemotherapy has not proven effective in hepatocellular carcinoma (HCC). Sorafenib is the only approved agent for advanced, unresectable disease. Current studies are evaluating a wide range of targeted agents covering the spectrum of molecular aberrations in HCC.…
Key points Image guided techniques are the most common invasive therapy for unresectable hepatocellular carcinoma (HCC). Level 1 evidence supports survival benefit chemoembolization. New embolic devices may offer benefits not currenlty realized. Background Hepatocellular carcinoma (HCC) is the fifth most…