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Primary bone and soft tissue malignancies Primary bone and soft tissue malignancies are a heterogeneous group of relatively rare tumors, most of them deriving from mesenchymal tissue (sarcomas). The reported international annual incidence for sarcomas ranges from 1.8 to 5…

Clinical management of malignancies of the chest Lung cancer Lung cancer is the leading cause of cancer deaths in men and women worldwide with a 5-year survival of only around 20% ( ). Cigarette smoking is the single most common…

Acknowledgments This work was in part supported by a grant from the National Cancer Institute, grant number R01CA269231, and the Sarcoma Foundation of America. We thank Mehdi Khalighi, Dawn Holley, and Kim Halbert from the PET/MRI Metabolic Service Center for…

Acknowledgments We would like to thank Sabine Frank, Susan Notohamiprodjo and Alberto Villagran for their assistance preparing this chapter. Introduction In recent years, numerous imaging modalities have been developed to diagnose cardiac disease noninvasively and to measure structural, functional, and…

Acknowledgments VG has received funding from the Swiss National Science Foundation (project n. 185028, 188355 and 169876), the Velux Foundation, the Schmidheiny Foundation and research/teaching support through her institution from Siemens Healthineers, GE Healthcare, Roche, Merck, Cerveau Technologies and Life…

Introduction The region of the head and neck involves complex anatomic structures, including the skull base, temporal bone, orbit, oral cavity, paranasal sinuses, and aerodigestive tract. Various kinds of pathology, including trauma, infection, congenital disease, and benign and malignant tumors…

Introduction to PET radiopharmaceuticals and radionuclides PET radiopharmaceuticals are radioactive tracers used for diagnostic purposes in PET imaging. They consist of two main components, a positron-emitting radionuclide and a tracer/carrier molecule that delivers the radioactive label to the target (…

Introduction Multimodal information is often required for diagnostic or research purposes as each imaging technique provides complementary data, for example about anatomy, physiology, or metabolism. Positron emission tomography (PET) measures the distribution and concentration of certain molecules in the body,…

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