Coronary artery disease (CAD) is a leading cause of global mortality. It results from atherosclerosis, which is a systemic and progressive disease involving the intimal layer of large- and medium-sized arteries. Atherothrombosis, defined as atherosclerotic plaque disruption (predominantly plaque rupture)…
Although death rates in industrialized countries have been consistently falling since the 1980s, atherosclerosis is now raging throughout the developing world. As a consequence the complications of atherosclerosis have become the leading cause of mortality and morbidity worldwide. Fundamentally, atherosclerosis…
Since the report published in 1968 by Favaloro about the use of saphenous veins to restore coronary artery blood flow in 171 patients, a large number of coronary artery bypass grafting (CABG) procedures have been performed worldwide. In the United…
A coronary stenosis may be observed during cardiovascular magnetic resonance (CMR) as an area of signal loss caused by turbulent flow, and although both the degree and the extent of signal loss are indicative of the severity of the stenosis,…
Chapter 23 reviewed the technical issues and solutions for coronary artery cardiovascular magnetic resonance (CMR) imaging. This chapter reviews the clinical data comparing coronary artery CMR with invasive x-ray coronary angiography for identification of anomalous coronary artery disease (CAD), characterization…
Despite significant efforts in prevention and treatment, coronary artery disease (CAD) remains the leading cause of death in the United States, accounting for one in every seven deaths. Each year nearly 700,000 Americans are estimated to have a new myocardial…
Left ventricular (LV) diastolic function has been recognized as an important factor in the pathophysiology of many common cardiovascular diseases. Dilated and hypertrophic cardiomyopathy (HCM), coronary artery disease (CAD), and systemic hypertension are all associated with abnormal LV filling dynamics.…
The detection of residual myocardial viability in a patient with regional or global severe left ventricular (LV) dysfunction is of clinical importance to plan the therapeutic strategy because revascularization of dysfunctional but viable myocardium may improve LV function. Several imaging…
Approximately 550,000 Americans will suffer an acute myocardial infarction (AMI) each year. Despite major advances in AMI therapies, mortality and incident heart failure (HF) remain significant problems. Five-year mortality is estimated at 36% in men and 47% in women. The…
Cardiovascular magnetic resonance (CMR) can characterize acute myocardial infarction (AMI) in unique ways and with high quality. Cine CMR can assess left ventricular (LV) volumes, ejection fraction (LVEF), and regional wall motion in ways comparable to a high-quality transthoracic echocardiogram.…