Definition A benign lesion of the prostate characterized by a biphasic population of small-sized glands and a cellular and/or hyalinized spindled cell stroma, the former of which can show myoepithelial differentiation (i.e., a metaplastic process). Clinical features You’re Reading a…
Definition Adenosis of the prostate is a pseudoneoplastic lesion, usually in the transition zone, that can mimic prostate adenocarcinoma and consists of a proliferation of crowded glands, arranged in a nodule but without significant cytologic atypia. A synonym is atypical…
Definition A benign lesion of the prostate composed of pale glands lined by epithelial cells with dense to vesicular crinkled nuclei and a scant amount of pale to clear cytoplasm, with the nuclei often touching the apical cytoplasmic borders. It…
Definition Morphologically distinct subtype of focal atrophy Also known as post atrophic hyperplasia Clinical features Epidemiology Present in a minority of prostatic needle biopsy and radical prostatectomy specimens Typically occurs in the elderly; uncommon in young men You’re Reading a…
Definition A distinct form of glandular atrophy characterized by cystically dilated glands with sharp luminal borders. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log…
Definition Small, benign glands arranged in nests with reduced cytoplasmic volume in luminal epithelial cells. Simple atrophy maintains relatively normal glandular spacing and reduced luminal diameter. Clinical features Epidemiology Typically affects the elderly with the prevalence and extent of gland…
Definition Granulomatous prostatitis induced by infectious agents. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
Definition Aggregate of lipid-laden histiocytes found within the prostatic stroma. Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
Definition Granulomatous inflammatory response seen after transurethral resection or needle core biopsy of the prostate gland. Clinical features Epidemiology Seen in men undergoing repeat transurethral resection (TUR). Rarely can be seen after prostate needle biopsy. Less than 1% of benign…
Definition Mixed inflammatory response owing to extravasated prostatic fluid, bacterial toxins, and cell debris. Clinical features Epidemiology Most commonly seen in the fifth and sixth decades. Present in 0.5%–3.4% of prostate specimens, and accounts for approximately two-thirds of all granulomatous…