Category Pathology

Cystitis cystica et glandularis

Definition Proliferative or reactive changes occurring in von Brunn nests, which become cystically dilated and acquire a luminal space (cystitis cystica) or undergo further glandular metaplasia (cystitis glandularis) Clinical features You’re Reading a Preview Become a Clinical Tree membership for…

von Brunn nests

Definition Reactive proliferative change in the form of solid urothelial nests beneath urothelium, seen along the entire urinary tract, considered a variant of the normal urothelial histology, and may also occur as a result of local inflammation. Clinical features Epidemiology…

Mixed epithelial and stromal tumor

Definition Tumor originating in the seminal vesicle with neoplastic stromal and epithelial component Also reported as epithelial-stromal tumor, cystic epithelial-stromal tumor, cystadenoma, cystomyoma, mesenchymoma, Müllerian adenosarcoma-like tumor, phyllodes tumor, or cystosarcoma phyllodes Clinical features You’re Reading a Preview Become a…

Seminal vesicle adenocarcinoma

Definition Adenocarcinoma arising in the seminal vesicle and recapitulating its architecture and immunoprofile Epidemiology Exceedingly rare You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log…

Amyloidosis

Definition Bilateral localized and isolated amyloid deposits in the subepithelial region of the seminal vesicles and ejaculatory systems (senile seminal vesicle amyloid) Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles…

Anatomy and histology of seminal vesicles

Definition Paired male accessory sex glands; produce an alkaline secretion known to constitute the bulk of the ejaculate, promote sperm function, and provide an assortment of potent antibacterial factors to the male genital tract. Seminal vesicles develop as outpouchings of…

Nonprostatic adenocarcinoma involving the prostate

Definition Metastatic adenocarcinomas to the prostate are secondary adenocarcinomas that have spread to the prostate gland via angiolymphatic invasion. More commonly, adenocarcinomas from contiguous organs (e.g., bladder and colorectum) directly invade the prostate. Clinical features Epidemiology Distant metastases to the…

Work-up of “vanishing” cancer in radical prostatectomy

Definition Inability to identify residual cancer in the final surgical specimen, despite complete sampling in patients undergoing radical prostatectomy for biopsy-confirmed prostate carcinoma Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited…

Genetics and genomics in prostate cancer

Prostate cancer genetics Prostate carcinoma is a multifactorial disease influenced by both environmental and genetic factors. Positive family history is the strongest epidemiological risk factor after advancing age and ethnic background. Prostate carcinoma can be divided into three groups: hereditary,…