Definition A germ cell tumor that predominantly affects young children and recapitulates the extraembryonic structures including the yolk sac, allantois, and extraembryonic mesenchyme Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited…
Definition Benign unilocular cyst lined by keratinizing stratified squamous epithelium which lacks skin adnexa or other teratomatous components Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you…
Definition A form of prepubertal-type teratoma composed of elements that replicate the structure of skin in an organoid arrangement No association with germ cell neoplasia in situ, dysgenetic gonads, or chromosome 12p amplification Clinical features Epidemiology Rare (less than 1%…
Definition A monodermal teratoma in the prepubertal testis is composed of low-grade, well-differentiated neuroendocrine tumor (or carcinoid tumor). Although most cases are pure carcinoid tumor, some are mixed with epidermoid/dermoid cysts or other teratomatous components. Clinical features You’re Reading a…
Definition Spermatocytic tumor, formerly known as spermatocytic seminoma, is a rare germ cell tumor distinct from classical seminoma both clinically and pathologically. Pathologically, it is characterized by three distinct cell types, lack of cytoplasmic glycogen, and scant to absent lymphocytic…
Definition Germ cell tumors that are partially or completely regressed, resulting in a scar or fibrotic area in the testis. Also known as “burned-out” germ cell tumors. Clinical features Epidemiology Partial or complete spontaneous regression occurs in <5% of germ…
Definition Germ cell tumors showing trophoblastic differentiation other than choriocarcinoma and non-trophoblastic tumors with syncytiotrophoblasts, including placental trophoblastic tumor (PSTT), epithelioid trophoblastic tumor (ETT) and cystic trophoblastic tumor (CTT) Clinical features You’re Reading a Preview Become a Clinical Tree membership…
Definition Malignant germ cell tumor that recapitulates the trophoblastic cells of extraembryonic chorion, including syncytiotrophoblast, cytotrophoblast, and intermediate trophoblast cells Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership…
Definition A teratoma develops a distinct secondary somatic (or non-germ cell) malignant component. Clinical features Epidemiology Only in postpubertal patients (age range, 15–68 years) Seen in 3%–6% of germ cell tumors (GCT) containing a teratomatous component You’re Reading a Preview…
Definition Testicular germ cell tumor composed of more than one histologic type of germ cell tumor Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a…