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D efinition — Infection of the uterus (endometrium) by Mycobacterium tuberculosis . Clinical Features Epidemiology Involvement of the uterus by tuberculosis (TB) is exceedingly rare, due to modern treatment. Patients with uterine involvement often have systemic (or miliary) disease. Uterine…

D efinition — Extensive necroinflammatory debris within the uterine cavity. Clinical Features Epidemiology Overall rare (0.1% to 0.5% of women) but more commonly occurs in postmenopausal women. Associated with a wide range of disorders, including cervical stenosis, leiomyomata, retained IUD,…

D efinition — Granular material that may be found in association with intrauterine devices. Clinical Features Epidemiology The finding of granular material associated with intrauterine device (IUD) use is not uncommon, happening in slightly less than 10% of patients. To…

D efinition — Chronic inflammatory process within the uterus often associated with infection. Clinical Features Epidemiology Chronic endometritis (CE) is thought to represent an infectious process. CE is strongly associated with the presence of pelvic inflammatory disease and acute salpingitis.…

D efinition — An endometrial polyp composed of benign smooth muscle and glands. Clinical Features Epidemiology Adenomyomatous polyps are a variant of endometrial polyp with smooth muscle differentiation. They are often found in association with conventional polyps. You’re Reading a…

D efinition — Endometrium with both secretory and proliferative pattern glands. Clinical Features Epidemiology True mixed-pattern endometrium is relatively uncommon and can be attributed to four likely causes: 1. Hormonal imbalance (therapy) 2. Irregular ovulation 3. Defects in follicle development…

D efinition —Artifactual compression of glands during the biopsy process. Clinical Features Epidemiology Telescoping artifact is common and can be identified in a large proportion of endometrial biopsies. You’re Reading a Preview Become a Clinical Tree membership for Full access…

D efinition —An exaggerated response to unopposed estrogen but lacking the features of endometrial intraepithelial neoplasia (EIN) (atypical hyperplasia). Clinical Features Epidemiology Most commonly seen at or around menopause with failed ovulation and persistent follicle. Common in polycystic ovarian syndrome…

D efinition —Alterations in the endometrium due to lack of ovulation and estrogenic effects of a persistent follicle. Clinical Features Epidemiology Most commonly seen at or around menopause with failed ovulation and persistent follicle. Common in polycystic ovarian syndrome (PCOS).…

D efinition — Scheduled menstrual breakdown and abnormal stromal breakdown histologically mimicking adenocarcinoma. Clinical Features Epidemiology The presence of stromal breakdown within an endometrial biopsy is relatively common; fortunately, however, extensive breakdown, mimicking neoplasia, is relatively uncommon. You’re Reading a…