See also Non-steroidal anti-inflammatory drugs (NSAIDs) General information Like other non-steroidal anti-inflammatory drugs (NSAIDs), ibuprofen is a potent inhibitor of prostaglandin synthesis, and many or all of its therapeutic and toxic effects are linked to this characteristic. The general impression…
See also Monoclonal antibodies General information Ibritumomab is a murine IgG 1 anti-CD20 antibody, the parent of the engineered chimeric antibody rituximab, a monoclonal antibody with mouse variable and human constant regions. It induces apoptosis and has antiproliferative effects. Ibritumomab…
General information Ibopamine is a dopamine derivative that has been studied in patients with congestive heart failure [ ] and has been used as a preoperative mydriatic for cataract surgery [ ] and to treat chronic refractory ocular hyptotony, although…
See also Anticholinergic drugs General information Hyoscine is an anticholinergic drug, a stereoisomer of atropine. It is available in different salts, hyoscine hydrobromide and hyoscine butylbromide. When given parenterally hyoscine butylbromide is effective but very short-acting; when given by mouth…
See also Antivenoms , Immunotherapy General information The Hymenoptera genus, one of the largest genera of insects, includes bees and wasps, sawflies and ants. The name comes from Greek words for a membrane (hymen) and a wing (pteron). Bee and…
See also Antihistamines General information Hydroxyzine is a first-generation antihistamine, a piperazine derivative, with antimuscarinic and sedative properties. Organs and systems You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If…
See also Cytotoxic and immunosuppressant drugs General information Hydroxycarbamide (hydroxyurea) is used to treat a variety of cancers, myeloproliferative disorders, and sickle cell disease, and has been studied in patients with HIV infection [ ]. It inhibits ribonucleotide reductase and…
General information Hydroquinone has been used in skin bleaching formulations for the treatment of hyperpigmentation and can cause short- and mid-term reactions like exogenous ochronosis and leukoderma en confetti, irritant reactions, and allergic reactions [ ]. Long-term adverse reactions such…
General information Intolerable adverse reactions or inadequate analgesia occur in 10–15% of patients with chronic pain given continuous intrathecal morphine. Hydromorphone is a semisynthetic derivative of morphine used extensively in the management of cancer pain. It is more soluble than…
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