See also Non-steroidal anti-inflammatory drugs (NSAIDs) General information Isoxepac has been used as an analgesic after joint surgery [ ] and in the management of rheumatoid arthritis [ ] and dysmenorrhea [ ]. You’re Reading a Preview Become a Clinical…
General information Isopropanolamine is used in cosmetics, hair perms, hair sprays, and in tanning lotions as a buffering agent. Derivatives of isopropanolamine have been developed as HIV protease inhibitors [ , ]. Occupational exposure to monoisopropanolamine can irritate the upper…
See also Anticholinergic drugs General information A 5–10 mg oral dose of the anticholinergic drug isopropamide iodide produces typical anticholinergic effects and has been used to treat a range of disorders of the gastrointestinal tract [ , ] and urinary…
See also Adrenoceptor agonists General information As a non-selective beta-adrenoceptor agonist, isoprenaline produces a wide range of adrenergic effects. Those that involve the heart present the most marked problems in practice. Doses of up to 10 micrograms/minute are used to…
See also Antituberculosis drugs General information Isoniazid is the hydrazide of isonicotinic acid. It is a first-line drug for treatment and prevention of tuberculosis. It is bactericidal for rapidly dividing mycobacteria, but bacteriostatic for “resting bacilli”. Among non-tuberculosis mycobacteria, only…
General information Isometheptene is an indirect sympathomimetic with a tyramine-like action and is also an agonist at alpha-adrenoceptors. It has been used as a non-prescription drug in the treatment of migraine [ , ], often in combination with other analgesics…
General information Isoflurane is a potent inhalation anesthetic. An isomer of enflurane, it has many of the same adverse effects. It is hardly metabolized (about 0.2%), which has encouraged its prolonged use as a sedative agent or bronchodilator in patients…
General information Isoetarine is a beta-adrenoceptor agonist bronchodilator given orally in a modified-release formulation [ ]. It is slightly more beta 2 -selective than isoprenaline but has a beta-blocking metabolite. When isoetarine was compared with salbutamol in the treatment of…
See also Aminoglycoside antibiotics General information Isepamicin is similar to amikacin but has better activity against strains that produce type I 6′-acetyltransferase. It can cause nephrotoxicity, vestibular toxicity, and ototoxicity. However, it is one of the less toxic of the…
See also Iron oxide General information Iron is a metallic element (symbol Fe; atomic no. 26). The symbol is derived from the Latin word for iron, ferrum. Iron is found widespread in nature in ores such as almandine hercynite (iron…