General information Lesopitron is a non-benzodiazepine anxiolytic drug. Its structure is similar to that of buspirone, and it is an agonist at central serotonin (5-HT 1A ) receptors [ ]. In a 6-week, double-blind, randomized, parallel, phase II, single-center, outpatient…
See also Calcium channel blockers General information Lercanidipine is a third-generation dihydropyridine for once-daily dosing in hypertension. It has similar antihypertensive efficacy and adverse effects to other calcium channel blockers [ ]. Drug studies You’re Reading a Preview Become a…
General information Lepirudin is a direct thrombin inhibitor obtained by recombinant technology from the medicinal leech and used for treatment of patients with heparin-induced thrombocytopenia and allergic reactions [ ]. An 85-year-old woman developed localized infiltrated plaques followed by a…
General information Lentinan is an immunomodulating glucan that is extracted from the mushroom Lentinus edodes. It has been used in small numbers of patients with gastric cancers [ ] and malignant effusions [ ]. It has also been used in…
See also Manitimus General information Teriflonumide (A77 1726) is the active metabolite of the prodrug leflunomide ( N -(4′-trifluoromethylphenyl)-5-methylisoxazole-4-carboxamide), an isoxazole derivative. [ ]. Mechanism of action Teriflunomide inhibits dihydro-orotate dehydrogenase, the rate-limiting enzyme in pyrimidine synthesis. It inhibits the…
You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
General information Lead is a heavy soft bluish-gray metal (symbol Pb; atomic no. 82) that is widespread as different salts in minerals such as chromite (oxide), crocoisite (chromate), Jamesonite and zinkenite (sulfides), mimetite (arsenate and chloride), pyromorphite (phosphate and chloride),…
General information Laxatives can be classified according to their several mechanisms of action: bulk-forming laxatives, such as bran, methylcellulose, Plantago extracts (ispaghula and psyllium), and sterculia; stimulant laxatives, such as the anthraquinones (senna and dantron), bisacodyl, docusate sodium (also a…
General information Lauromacrogols are mixtures of monolauryl esters of macrogols. They have the following general formula: C 12 H 25 (OCH 2 CH 2 ) n OH. Each is named after the number n in its formula. For example, in…
General information The genera in the family of Lauraceae ( Table 1 ) include bay, cinnamon, laurel, and sassafras. Table 1 Genera of Lauraceae Aniba (aniba) Beilschmiedia (beilschmiedia) Cassytha (cassytha) Cinnamonum (cinnamon) Cryptocarya (cryptocarya) Endiandra (walnut) Eusideroxylon (ironwood) Laurus (laurel)…