Category Internal Medicine

Cocaine

General information Cocaine is an alkaloid derived from the plant Erythroxylon coca and other Erythroxylon species in South America. The leaves contain cocaine as the principal alkaloid, plus a variety of minor alkaloids. Only decocainized coca products are legal in…

Cobalt

See also Chromium General information Cobalt is a metallic element (symbol Co; atomic no. 27). It is an important constituent of the cobalamins (vitamin B 12 ) and is found as arsenates and arsenides in naturally occurring minerals such as…

Coagulation proteins

See also Individual agents General information The major coagulation and fibrinolytic proteins are listed in Table 1 . Table 1 Proteins involved in coagulation and fibrinolysis Protein (synonym) Function Coagulation proteins Factor I (fibrinogen) Activated to fibrin Factor II a…

Clusiaceae

General information The genera in the family of Clusiaceae ( Table 1 ) include St John’s wort and brindleberry (gamboge). Table 1 Genera of Clusiaceae Calophyllum (calophyllum) Hypericum (St John’s wort) Platonia (platonia) Clusia (attorney) Mammea (mammea) Triadenum (marsh St…

Clozapine

See also Neuroleptic drugs General information Clozapine is a dibenzodiazepine, an atypical neuroleptic drug with a high affinity for dopamine D4 receptors and a low affinity for other subtypes [ ]. It is also an antagonist at alpha-adrenoceptors, 5-HT2A receptors,…

Cloximate

See also Non-steroidal anti-inflammatory drugs (NSAIDs) General information Cloximate is an oxime ether derivative non-steroidal anti-inflammatory drug (NSAID) [ ]. It was approved in only a few countries, and experience with it is limited. The usual adverse effects of NSAIDs…

Clotiapine

See also Neuroleptic drugs General information Clotiapine is a dibenzothiazepine neuroleptic drug [ ]. Organs and systems You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member.…

Clopidogrel

General information Clopidogrel is a thienopyridine compound, structurally related to ticlopidine, which inhibits ADP-induced platelet aggregation [ ]. Its efficacy in stroke, myocardial infarction, and other vascular causes of death has been demonstrated in the CAPRIE Study [ ], a…