Key Points Incidence Colorectal cancer is the fourth most common form of cancer worldwide, with an estimated 800,000 new cases diagnosed each year, accounting for roughly 10% of all cancers. Approximately two-thirds of cases occur in the colon and one-third…
Key Points Epidemiology/Etiology In 2018, it is estimated that nearly 140,000 patients will be diagnosed with colon or rectal cancer and 50,000 deaths will occur in the United States. Linkage between diet and environmental factors with colon cancer is supported…
Key Points Incidence Globally, hepatobiliary cancer is the sixth most common cause of cancer and the second most common cause of cancer death. In 2018, the expected incidence of hepatobiliary cancer in the United States was 54,410 cases, with 33,990…
Key Points Incidence and Epidemiology In the United States in 2018, an estimated 55,440 patients will be diagnosed with pancreatic cancer (PCA) and 44,330 will die of the disease. PCA is the 12th most commonly diagnosed cancer and the 4th…
Key Points Incidence For 2019, the predicted incidence of esophageal and gastric cancers in the United States is projected to be 17,650 and 27,510 cases, respectively. The predicted number of deaths is 16,080 and 11,140, respectively. The site of origin…
Gastrointestinal (GI) cancer continues to be a common health problem. Approximately 319,160 new cases of GI malignant disease were estimated to occur in the United States in 2018 with an associated 160,820 deaths. Although colorectal tumors account for almost 50%…
Key Points Incidence Three distinct neoplasms are discussed in this chapter: thymoma, bronchopulmonary carcinoid, and malignant pleural mesothelioma. The overall incidence of thymoma in the United States is 0.15 cases per 100,000 persons. Thymoma is the most common tumor of…
Key Points Incidence In the United States, approximately 228,150 cases of lung cancer and approximately 142,670 deaths were projected from lung cancer in 2019. Incidence is decreasing in the United States while increasing worldwide, reflecting patterns in tobacco use. Routine…
Key Points Incidence Small cell lung cancer (SCLC) represents about 15% of over 230,000 annual lung cancer diagnoses in the United States. Only about one-third present without metastatic disease. Biological Characteristics SCLC is a high-grade tumor of the lung, with…
Primary thoracic neoplasms are reviewed in detail in the chapters of this section. In this overview, we consider developments and controversies in the diagnosis and treatment of non–small cell lung cancer (NSCLC), small cell lung cancer (SCLC), thymic tumors, pulmonary…