See also : Anticholinergic drugs General information Emepronium bromide is an anticholinergic drug. Doses of 200 mg tds (sometimes with a double dose in the evenings) are useful in relieving urinary frequency. It causes the expected milder anticholinergic adverse effects.…
See also Antihistamines General information Emedastine is a potent second-generation antihistamine with proven efficacy in allergic conjunctivitis [ ]. Drug studies You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If…
General information Eflornithine is a specific irreversible inhibitor of ornithine decarboxylase, the enzyme involved in the first step of mammalian polyamine biosynthesis [ ]. Decarboxylation of ornithine is an obligatory and rate-limiting step in the biosynthesis of polyamines, such as…
See also Non-nucleoside reverse transcriptase inhibitors (NNRTIs) General information Efavirenz is a non-nucleoside reverse transcriptase inhibitor with excellent inhibitory activity against HIV-1. Its most frequent adverse effects involve the central nervous system and the skin [ ]. At the start…
General information Efalizumab is a humanized monoclonal antibody that inhibits T cell activation by binding to lymphocyte function-associated antigen-1 (LFA-1), the alpha subunit of CD11a, and consequently inhibits T-cell activation [ ]. LFA-1 binds to intracellular adhesion molecule-1, an important…
See also : Monoclonal antibodies General information Edrecolomab (17–1A antibody), a mouse monoclonal antibody, has been used in the adjuvant treatment of colorectal cancer. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles…
General information Edetic acid is a metal chelator. The effect of an intravenous dose of 1 g of calcium disodium edetate on the urinary excretion on the elements aluminium, boron, barium, calcium, copper, iron, lead, magnesium, manganese, phosphorus, potassium, silicon,…
General information The echinocandins are a class of semisynthetic antifungal lipopeptides that are structurally characterized by a cyclic hexapeptide core linked to a variably configured lipid side chain. The echinocandins act by non-competitive inhibition of the synthesis of 1,3-α- d…
General information Ecabet is an anti-ulcer agent that works by irreversibly inhibiting urease and ATPase in Helicobacter pylori under acidic conditions [ , ]. It may also impair bacterial adhesion to gastric epithelia [ ]. It has bactericidal activity against…
See also Antihistamines General information Ebastine is a second-generation antihistamine with proven efficacy in the treatment of allergic disease [ ]. It is rapidly absorbed after oral administration, and undergoes extensive first-pass metabolism by CYP3A4 to its active carboxylic acid…