General information Ganciclovir (dihydroxypropoxymethylguanine) is a nucleoside analogue with antiviral activity in vitro against herpesviruses. Intracellular phosphorylation of ganciclovir to its triphosphate derivative, which acts as a competitive inhibitor of deoxyguanosine triphosphate, leads to the inhibition of viral DNA synthesis.…
General information Sodium gammahydroxybutyrate (GHB or sodium oxybate) is an endogenous compound, a precursor of GABA, which increases the release of dopamine and acetylcholine in the brain. It was first synthesized in 1960 as a potential anesthetic, and was popular…
General information Gallium is a metallic element (symbol Ga; atomic no. 31) that has been used in the form of a radiopharmaceutical ( 67 Ga as the citrate) in diagnostic imaging of cancers, inflammation, and infection [ ]. The mechanisms…
General information Gallamine is a non-depolarizing muscle relaxant. For intubation, a dose of about 2 mg/kg (some authors say 3–4 mg/kg) is necessary, and the duration of effect is then similar to the usual intubating doses of d -tubocurarine or…
General information Gadolinium chelates for MRI are inert, non-metabolized, small molecules, with essentially the same pharmacokinetic properties as the iodinated contrast agents [ ]. They are rapidly distributed in the extracellular fluid spaces, both intravascular and extravascular, although they do…
See also Antiepileptic drugs General information Gabapentin is used as adjunctive treatment for partial seizures and may be useful in some non-epileptic disorders, such as neuropathic pain. It has a favorable tolerability profile and is devoid of significant interactions with…
General information Fusidic acid is the best-known representative of a group of antibiotics with steroid structures, which are eliminated primarily by biliary excretion as microbiologically inactive metabolites. The antibacterial action of fusidic acid is bacteriostatic, although it can be bactericidal…
General information Furosemide is one of the so-called high-ceiling or loop diuretics, which can achieve a much greater peak diuresis than the thiazides. It is widely and frequently used both orally and parenterally over a wider dosage range than the…
General information Furazolidone has been used in the treatment of giardiasis. Adverse reactions are usually mild and transient: abdominal discomfort, nausea, and vomiting; the urine may be dark-colored [ ]. Metabolites of furazolidone inhibit monoamine oxidase [ , ] and…
General information Furaltadone, 5-morpholinomethyl-3-(5-nitrofurfuryliden-amino)oxazolidin-2-one), is a crystalline antibiotic powder that is added to animal feeds. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in…