See also HIV protease inhibitors General information The marketing authorization of amprenavir (Agenerase) was withdrawn for commercial reasons at the request of the marketing authorization holder in 2011. Since fosamprenavir is still marketed and is a prodrug for amprenavir, adverse…
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General information Having a broad-spectrum fungicidal activity, amphotericin remains the mainstay of treatment of most invasive fungal infections. Compared with conventional amphotericin B deoxycholate, other lipid formulations of amphotericin (amphotericin B colloidal dispersion, amphotericin B lipid complex, and liposomal amphotericin…
General information Note on spelling In International Non-proprietary Names the digraph -ph- is usually replaced by -f-, although usage is not consistent, and -ph- is used at the beginnings of some drug names (for example, compare fenfluramine and phentermine) or…
See also Tricyclic antidepressants General information Amoxapine has a tricyclic nucleus with a modified piperazine side chain and is closely related to the neuroleptic drug loxapine [ ]. In animals, amoxapine has no antiserotonergic properties and less anticholinergic activity than…
General information Amopyroquine is a 4-aminoquinoline, structurally related to amodiaquine. It is not a new compound, but it is of renewed interest as a result of the extensive occurrence of resistance to chloroquine and the adverse effects of prophylactic amodiaquine.…
General information Amodiaquine is a Mannich base derivative related to chloroquine. While it is generally considered equivalent to chloroquine, more recent studies have shown that amodiaquine is superior to chloroquine in tackling resistant strains of Plasmodium falciparum , although there…
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General information Ammonium tetrathiomolybdate is a copper chelator that has been used to treat Wilson's disease [ ]. It also inhibits angiogenesis, perhaps by inhibiting copper ion-dependent membrane translocation involving a non-classical secretory pathway [ ], and inhibits NFκB […
General information Ammonium chloride is used as an expectorant in productive cough. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here