See also individual agents; Antifungal azoles and other antifungal drugs for topical use General information The antifungal azoles are a class of synthetic compounds that have one or more azole rings and a more or less complex side chain attached…
See also individual agents General information Some of the drugs that are used to treat epilepsy can be grouped into classes (carbamazepine and its analogue oxcarbazepine, barbiturates, hydantoins, benzodiazepines, and succinimides), while others (for example valproate, felbamate, gabapentin, levetiracetam, lamotrigine,…
General information Classification Drugs used in dysrhythmias can be classified in different ways, the usual classification being according to their effects on the cardiac action potential [ ], as shown in Table 1 . Table 1 Electrophysiological classification of antidysrhythmic…
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See also individual agents General information There are many anticholinergic drugs, some structurally related to atropine, others quaternary ammonium compounds or tertiary amines ( Table 1 ). Although many of these products are claimed to have superior efficacy, specificity, or…
See also Monoclonal antibodies General information BG9588 is an anti-CD40L antibody. The CD40–CD40L interaction plays a significant role in the production of autoantibodies and tissue injury in lupus nephritis [ ]. You’re Reading a Preview Become a Clinical Tree membership…
See also individual agents General information Drugs that are used in the treatment of angina pectoris include agents from the following groups: nitric oxide donors; beta-blockers; calcium channel blockers; potassium channel activators. Safety factors that govern the choice of antianginal…
See also individual agents General information Antiandrogens include steroids, such as cyproterone acetate, and non-steroidal agents, such as bicalutamide, flutamide, nilutamide, and abiraterone. They have different endocrine effects and therefore different adverse effects [ ]. Cyproterone acetate tends to result…
See also Vaccines General information Inactivated anthrax vaccine is mainly used for protection against occupational anthrax exposure. A complete vaccine series consists of three 0.5-ml subcutaneous doses at 2-week intervals, followed by three additional doses 6, 12, and 18 months…
See also Anthracyclines and Cytostatic and immunosuppressant drugs General information Liposomes are microscopic particles composed of a lipid bilayer membrane enclosing active drug in a central aqueous compartment [ ]. The aim of liposomal encapsulation of a drug is to…