Summary of Key Points The National Lung Screening Trial has definitively shown a reduction in lung cancer mortality in a research setting but effective implementation of a lung cancer screening program needs to be evaluated in different health-care communities. Selection…
Summary of Key Points While 85% to 90% of lung cancer is attributable to cigarette smoking, substantial evidence exists to support genetic susceptibility to this disease. A family history of lung cancer is associated with a 1.5 to 4-fold increased…
Summary of Key Points Epidemiology of lung cancer is still changing: in the last 10 years lung cancer became the first cause of cancer-related deaths in both men and women in many countries, while having previously been a rare disease…
Summary of Key Points The known or suspected etiologic factors for lung cancer arising in never-smokers are weak carcinogens or rare factors, which cannot explain the relatively high frequency of cancer in never-smokers. This also applies to environmental tobacco smoke.…
Summary of Key Points Addressing tobacco dependence in patients with cancer increases the quality of care by reducing their risk for treatment complications, improving their prognosis, and reducing the risk of disease recurrence and second primary cancers. Smoking cessation after…
Summary of Key Points Smoking is the predominant risk factor for development of lung cancer. As tobacco is introduced to societies, common patterns emerge. Typically, it is first used in men, then later in women. A 20- to 25-year lag…
Summary of Key Points Lung cancer incidence and mortality has declined among men in many countries, following a decline in the prevalence and level of smoking. Among women, lung cancer incidence and mortality is still increasing in many countries and…
Key Points Incidence The age-adjusted incidence of mycosis fungoides (MF) is approximately 6.4 cases per million. Three thousand cases per year are diagnosed in the United States, representing 72% of cutaneous T-cell lymphomas. Biologic Characteristics Mycosis fungoides is a chronic…
Key Points Incidence and Epidemiology More than 32,100 new cases of multiple myeloma (MM) are diagnosed annually in the United States. MM accounts for 1.8% of all new cancers and 2.1% of cancer-related deaths. The rate in blacks is twice…
Key Points Epidemiology and Incidence There were an estimated 74,680 new cases of lymphoma and 19,910 deaths in the United States in 2018. The incidence is increasing in many countries, including the United States. The most common types are diffuse…