Uropathology

Intestinal metaplasia

Definition Replacement of the urothelium, either in the surface or in the glandular elements of cystitis glandularis, by colonic-type mucosa (goblet cells) Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles…

Squamous metaplasia

Definition Metaplastic process in which the normal urothelium is replaced by either keratinizing or nonkeratinizing stratified squamous epithelium Clinical features Epidemiology More common in women than men Typically affects older adults Often a response to urothelial injury (e.g., chronic infection,…

Cystitis cystica et glandularis

Definition Proliferative or reactive changes occurring in von Brunn nests, which become cystically dilated and acquire a luminal space (cystitis cystica) or undergo further glandular metaplasia (cystitis glandularis) Clinical features You’re Reading a Preview Become a Clinical Tree membership for…

von Brunn nests

Definition Reactive proliferative change in the form of solid urothelial nests beneath urothelium, seen along the entire urinary tract, considered a variant of the normal urothelial histology, and may also occur as a result of local inflammation. Clinical features Epidemiology…

Mixed epithelial and stromal tumor

Definition Tumor originating in the seminal vesicle with neoplastic stromal and epithelial component Also reported as epithelial-stromal tumor, cystic epithelial-stromal tumor, cystadenoma, cystomyoma, mesenchymoma, Müllerian adenosarcoma-like tumor, phyllodes tumor, or cystosarcoma phyllodes Clinical features You’re Reading a Preview Become a…

Seminal vesicle adenocarcinoma

Definition Adenocarcinoma arising in the seminal vesicle and recapitulating its architecture and immunoprofile Epidemiology Exceedingly rare You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log…

Amyloidosis

Definition Bilateral localized and isolated amyloid deposits in the subepithelial region of the seminal vesicles and ejaculatory systems (senile seminal vesicle amyloid) Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles…

Anatomy and histology of seminal vesicles

Definition Paired male accessory sex glands; produce an alkaline secretion known to constitute the bulk of the ejaculate, promote sperm function, and provide an assortment of potent antibacterial factors to the male genital tract. Seminal vesicles develop as outpouchings of…

Nonprostatic adenocarcinoma involving the prostate

Definition Metastatic adenocarcinomas to the prostate are secondary adenocarcinomas that have spread to the prostate gland via angiolymphatic invasion. More commonly, adenocarcinomas from contiguous organs (e.g., bladder and colorectum) directly invade the prostate. Clinical features Epidemiology Distant metastases to the…