Textbook of Critical Care

Management of acute pain in the intensive care unit

Introduction Pain management in the critically ill patient is complex. Each patient brings a unique set of sociodemographic, pharmacokinetic, and pharmacogenomic variables that are coupled with underlying psychosocial and medical comorbidities. These not only influence a patient’s response to painful…

Agitation and delirium

Agitation and delirium are commonly encountered in the intensive care unit (ICU). Although frequently underrecognized, delirium is present in up to 80% of critically ill adults on mechanical ventilation when routinely assessed. Delirium and agitation are more than just an…

Sudden deterioration in neurologic status

Patients admitted to the intensive care unit (ICU) with critical illness or injury are at risk for neurologic complications. A sudden or unexpected change in the neurologic condition of a critically ill patient often heralds a complication that may cause…