Meningiomas are intracranial, extra-axial lesions that represent about one-third of all primary brain tumors, and over a half of noncancerous central nervous system (CNS) neoplasms. Falcine meningiomas are relatively rare. They arise from the falx cerebri and make up approximately…
Acknowledgment The Intramural Research Program of the National Institute of Neurological Disorders and Stroke at the National Institutes of Health supported portions of this manuscript. Epidemiology and Significance Meningiomas are the most common primary brain and central nervous system tumors…
Tumors of the fourth ventricle offer a unique challenge to the neurosurgeon because they lie deep in the brain in proximity to a number of vital structures. Although recent diagnostic and therapeutic advances have dramatically improved outcome for patients affected…
History Pineal region tumors encompass a diverse group of tumors that can arise from pineal parenchymal cells, supporting cells of the pineal gland, or glial cells from the midbrain and medial walls of the thalamus. These tumors occupy a central…
Introduction Endoscopic surgery for intraventricular brain tumors is a logical application of endoscopic technology. Because of the central and deep location of intraventricular brain tumors, conventional neurosurgical approaches have a relative increase in potential morbidity. Traditional approaches involve a craniotomy…
The majority of tumors of the lateral and third ventricles are benign or low-grade lesions. Because of their relatively slow growth rate, these lesions may reach several centimeters in size before patients present with neurologic dysfunction. The most common clinical…
Introduction Deep-seated brain lesions include a variety of pathologies, including benign and malignant brain tumors, vascular malformations, and intracranial hemorrhages (ICHs), among others. A deep-seated location is a nebulous term, but generally refers to any location below the deepest sulcal…
Craniopharyngiomas are benign tumors originating from squamous epithelial remnants of Rathke pouch that can arise anywhere along the axis from the nasopharynx to the hypothalamus. , Their consistency can be cystic, solid, or a combination of both, and there is…
Introduction and Epidemiology The most common tumors affecting the sellar, suprasellar, and parasellar regions include pituitary adenomas, Rathke cleft cysts, craniopharyngiomas, meningiomas, germ cell tumors, and gliomas involving the hypothalamus or optic chiasm. Management is dictated according to each specific…
The use of the endonasal pathway for skull base surgery was initially reported in 1909 by Hirsch, who performed his first pituitary surgery in Vienna by approaching the sella through an endonasal route using multiple-staged operations with unenhanced visualization. Despite…