Abbreviations A1AT alpha-1 antitrypsin DIOS dysmetabolic iron overload syndrome DMT1 divalent metal transporter 1 FPN ferroportin HH hereditary hemochromatosis HIC hepatic iron concentration HII hepatic iron index HJV hemojuvelin IRIDA iron-refractory iron-deficient anemia MHC major histocompatibility complex NAFLD nonalcoholic fatty…
Abbreviations ABC ATP-binding cassette CF cystic fibrosis CFTR cystic fibrosis transmembrane conductance regulator MBL2 mannose-binding lectin 2 PH prolyl hydroxylase TGFβ transforming growth factor β TIMP tissue inhibitor of matrix metalloproteinase TNFα tumor necrosis factor α UDCA ursodeoxycholic acid Cystic…
Abbreviations AAT alpha-1 antitrypsin ER endoplasmic reticulum PAS periodic acid–Schiff Pi protease inhibitor Alpha-1 antitrypsin (AAT) is the most abundant protease inhibitor and the second most abundant protein in plasma. It is produced predominantly by the liver and in smaller…
Abbreviations ALT alanine aminotransferase AMA antimitochondrial antibody ANA antinuclear antibody AST aspartase aminotransferase FDA Federal Drug Administration HAV hepatitis A virus HBV hepatitis B virus HCV hepatitis C virus ICC Indian childhood cirrhosis PCR polymerase chain reaction SMA smooth muscle…
Abbreviations ALF acute liver failure BASD bile acid synthetic defect CDG congenital disorders of glycosylation CoA coenzyme A FAO fatty acid oxidation mDNA mitochondrial DNA nDNA nuclear DNA OTC ornithine transcarbamylase PAS periodic acid–Schiff PFIC progressive familial intrahepatic cholestasis PH…
Abbreviations CDG congenital disorders of glycosylation CE-ESI-MS capillary electrophoresis–electrospray ionization–mass spectrometry GC-MS gas chromatography–mass spectrometry HPLC high-performance liquid chromatography MALDI matrix-assisted laser desorption/ionization MCAD medium chain acyl-CoA dehydrogenase MS/MS tandem mass spectrometry MSUD maple syrup urine disease mtDNA mitochondrial DNA…
Abbreviations AIH autoimmune hepatitis ALGS Alagille syndrome CMV cytomegalovirus ERK extracellular signal-regulated kinases GGT gamma glutamyltransferase HIDA hepatobiliary iminodiacetic acid JAG1 jagged-1 LCH Langerhans cell histiocytosis MAPK mitogen-activated protein kinases MAP2K1 mitogen-activated protein kinase kinase 1 NISCH neonatal sclerosing cholangitis…
Abbreviations CT computed tomography FDG fluorodeoxyglucose FNH focal nodular hyperplasia HCC hepatocellular carcinoma HVTT hepatic vein transit time IVIM intravoxel incoherent motion MRE magnetic resonance elastography MRI magnetic resonance imaging MRS magnetic resonance spectroscopy PET positron emission tomography RF radiofrequency…
Abbreviations AAT alpha-1 antitrypsin AIH autoimmune hepatitis ALP alkaline phosphatase ALT alanine aminotransferase AMA antimitochondrial antibodies ANA antinuclear antibodies anti-ASGPR antibodies to asialoglycoprotein receptor anti-HBc antibody to hepatitis B core antigen anti-LCA1 antibody to liver-specific cytosol antigen type 1 anti-LKM1…
Abbreviations ALF acute liver failure ALFSG Acute Liver Failure Study Group APACHE Acute Physiology and Chronic Health Evaluation HAV hepatitis A virus HBeAg hepatitis B e antigen HBV hepatitis B virus HCV hepatitis C virus HE hepatic encephalopathy HELLP hemolysis,…