Meyler's Side Effects of Drugs

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General information Brimonidine is a highly selective potent α 2 -adrenoceptor agonist, which is distinguished from clonidine by a chemical modification that reduces its ability to cross the blood–brain barrier. Like apraclonidine, brimonidine has been used to treat glaucoma. However,…

General information Bretylium, originally introduced as a hypotensive agent but no longer used as such, has not been extensively used as an antidysrhythmic drug. Its clinical pharmacology, uses, efficacy, and adverse effects have been reviewed [ ]. Adverse reactions have…

General information Brequinar (DUP 785, NSC 368390) is a quinoline carboxylic acid derivative that inhibits pyrimidine synthesis by inhibiting dihydro-orotate dehydrogenase. It was originally developed as an anticancer drug, but has also been investigated for its immunosuppressant activity after transplantation.…

General information The genera in the family of Brassicaceae ( Table 1 ) include various types of brassica (cabbage, broccoli, brussels sprouts, kale, kohlrabi, pak choi, rape, turnip), mustard, and cress. Table 1 Genera of Brassicaceae Alliaria (alliaria) Neobeckia (lake…

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General information Botulinum toxins A and B, which are produced by the bacterium Clostridium botulinum , are used for the treatment of facial rhytides (for example, lateral orbital wrinkles, lower eyelid wrinkles, and labial lines), by producing weakness or paralysis…

See also Endothelin receptor antagonists General information Bosentan is an endothelin-A and endothelin-B receptor antagonist. It is effective in pulmonary arterial hypertension [ , ] and has been marketed for this indication. The studies showed an improvement in exercise capacity…

See also Anticholinergic drugs General information Bornaprine, a synthetic quaternary ammonium compound, has been used as an anticholinergic drug in treating Parkinson’s disease [ , ]. It has also been used to treat hyperhidrosis [ ]. Its adverse effects are…

General information In the past, boric acid was falsely considered to be relatively non-toxic, and had an unwarranted reputation as a germicide. However, it is only bacteriostatic, even in a saturated aqueous solution, and can cause adverse reactions. Boric acid…