Risk For live births: 1:10,000; equal male to female prevalence Associated with younger maternal age May not be identified until later in life Perioperative Risks Reduced cortisol stress response in undiagnosed or untreated pts. Hormone tests may be normal in…
Risk Multiple genetic factors; mostly sporadic with limited familial inheritance Range: 1:10,000-30,000 newborns Perioperative Risks Variable phenotypic expression and organ involvement Increased incidence of additional developmental abnormalities Depend upon severity of disease and comorbidities, which may include elevated ICP; craniofacial,…
Risk Seroprevalence increases with age and low socioeconomic status in USA: From 58.9% in those aged ≥6 y to 90.8% in those ≥80 y. Also higher in non-Hispanic blacks, Mexican Americans, and women. Severe disease from CMV is rare in…
Acknowledgment The authors wish to acknowledge the contributions to the previous edition of this chapter by Daniel Roke and John Algren. Risk Prevalence ranges from 1:2500 births in white population to 1:17,000 in African Americans; prevalence growing faster than incidence…
Risk Potent rapid-onset toxin, especially with inhalation of HCN (volatile liquid). May be absorbed through mucous membranes; CN ingestion results in slower onset. Diffuses rapidly through body with high intracellular fixation to cytochrome aa 3 in cellular mitochondria to paralyze…
Risk Onset generally occurs in third and fourth decades. Approximately 3–5 times more common in women than men. 5-y mortality rate from adrenal carcinomas has been estimated to be >70%. Perioperative Risks Lyte abnormalities Consequences of untreated Htn Hyperglycemia Cardiovascular…
Risk In general population: 0.4–1.3 cases per 100,000; AIDS pts: 2–7 cases per 1000. Impact of cryptococcosis: Approximately 625,000 deaths each year worldwide. Underlying immunocompromised conditions and risk factors: AIDS, systemic lupus erythematous, prolonged treatment with corticosteroids, organ transplantation, advanced…
Risk Represents approximately 4.8% of cases of craniosynostosis at birth. Birth prevalence of 1.6:100,000 births. Estimated prevalence in general population of Europe is 0.9:100,000. No race predilection. Perioperative Risks Difficult BMV, difficult intubation, massive blood loss, arterial gas embolism Worry…
Risk Children between 6 mo-6 y are at risk (6 mo–3 y at greatest risk). Children with underlying airway abnormalities (e.g., subglottic stenosis) or difficult intubations (e.g., micrognathia) and symptoms are at increased risk and require particular planning. Perioperative Risks…
Risk Incidence of 3.1–14.6 cases per 100,000 person-years; prevalence of 26–201 cases per 100,000 persons. Incidence and prevalence are increasing worldwide; incidence is highest in North America and Northern Europe. Race: White >African American >Hispanic and Asian populations for risk.…