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Risk Genetic disease with reported annual incidence of approximately 1:100,000, but rarity may lead to underestimation of true prevalence Panethnic Perioperative Risks Autonomic instability, particularly with neuraxial anesthesia Cardiovascular instability from conduction abnormalities and structural heart disease Periop stroke in…

Risk Prevalent in children 1–7 y; sometimes called supraglottitis, it does occur in adults (decreasing incidence in children >3 y related to vaccines against Haemophilus influenzae type B, but still found, particularly if pt is not immunized). Adult incidence remains…

Risk 1:17,000, 50% dystrophic form Racial distribution equal Perioperative Risks Difficult IV access, airway, intraop positioning, reflux, steroid dependence, intraop hemorrhage, sepsis, iatrogenic corneal abrasion, blister formation, and airway obstruction Worry About Problems similar to those found in pts with…

Risk Incidence: 3–10:100,000 population. Rheumatic heart disease is a key risk factor in lower-middle income countries. Valvular and cyanotic heart disease, DM, cancer, and IV drug use are risk factors in higher income countries. Perioperative Risks Septic embolization to other…

Risk 4% of all congenital heart disease and 0.3–0.4:1000 live births 40–50% of AV canal defects are associated with trisomy 21 Perioperative Risks Paradoxical air embolism Shunt reversal (from left to right to right to left) because of vasodilating volatile…

Risk After successful prehospital cardiac resuscitation: 59–65% of pts remain comatose. 0–5% of successful resuscitations result in chronic vegetative state. Perioperative Risks Worsening of neurologic status; blindness most common residuum. Postpone surgery in all but emergency situations. Do what is…

Risk 3.4– 11% of medical ICU admissions 12–33% of multiple-organ dysfunction pts Perioperative Risks With predisposing conditions (e.g., hepatic insufficiency), risk of developing or exacerbating metabolic encephalopathy Increasing severity of preexisting encephalopathy Worry About Worsening hepatic insufficiency causing hepatic encephalopathy…

Risk Chronic Htn, renal disease (particularly end-stage renal disease), malignancy, sympathomimetic drugs, and a history of transplantation and immunosuppressive therapies Perioperative Risks Increased risk of myocardial ischemia, ventricular dysrhythmias, HF, aortic dissection, cerebral hemorrhage, coma, long-term neurologic disability, renal failure,…

Risk Age; animal contact and occupational exposure to animals; ingestion of raw, partially cooked meat, fish, reptiles, or unpasteurized milk; insect contact; laboratory workers; healthcare workers; person-person transmission; recent vaccination and unvaccinated status; season (late summer/early fall, winter); travel and…

Risk Incidence in USA: 4.7 million. Prevalence, incidence, and mortality increase with age. Higher in males than females. Higher in whites than nonwhites. Perioperative Risks Intraop bronchospasm N 2 O expansion of bullae Postop respiratory failure Postop pulm infection Worry…