Physical Address
304 North Cardinal St.
Dorchester Center, MA 02124
IBC
You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
Review Question Answers
Chapter 1 1. a. Cardiac relaxation is regulated by NO. ROS can affect NO-related signaling at multiple sites. NO is generated by NO synthase (NOS), which requires tetrahydrobiopterin as a cofactor for the reaction. Hypertension and activation of the renin-angiotensin system…
Cases of Diastolic Heart Failure
Case 1 35-Year-Old African American Man With Suspected Left Ventricular Hypertrophy History: 35-year-old African American athlete referred for evaluation of suspected left ventricular hypertrophy based on an electrocardiogram (ECG) obtained during his annual screening. He is otherwise completely asymptomatic. Past…
Future Therapies in HFpEF
Introduction The treatment of diastolic heart failure (HF), also known as heart failure with preserved systolic function (HFpEF), has been challenging, partly because there is a lack of consensus regarding the definition of the disease entity as well as a…
Echo-Based Approach to the Management of Heart Failure With Preserved Ejection Fraction
Case Study A 76-year-old female with a history of heart failure with preserved ejection fraction (HFpEF), type 2 diabetes mellitus, obesity, hypertension, and chronic back pain is referred to you from her primary care provider. She was diagnosed with HFpEF…
General Treatment of Heart Failure With Preserved Ejection Fraction and Randomized Trials
Case Study A 45-year-old male presents for a 1-month follow-up visit after an index hospitalization for dyspnea and peripheral edema, at which time he was found to be hypertensive. He has no known diabetes or coronary artery disease (CAD). His…
Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction
Abbreviations HFpEF heart failure with preserved ejection fraction HFrEF heart failure with reduced ejection fraction mPAP mean pulmonary arterial pressure PA pulmonary arterial/artery PCWP pulmonary capillary wedge pressure PH pulmonary hypertension PVR pulmonary vascular resistance RV right ventricle / right…
Perioperative Assessment of Diastolic Function
Case Study A 75-year-old female presents for coronary artery bypass grafting (CABG) for treatment of unstable angina secondary to severe three-vessel coronary artery disease. The patient reports a history of hypertension, hyperlipidemia, and diabetes mellitus. Preoperative transthoracic echocardiogram demonstrated normal…
Aging and Heart Failure With Preserved Ejection Fraction
Case Study A 68-year-old woman with a history of hypertension (HTN) presents to clinic with dyspnea on exertion. She is an avid gardener and has been unable to keep up with her weeding over the past few years. Otherwise, she…
Chronotropic Incompetence and Pacing in HPEF Heart Failure with Preserved Ejection Fraction
Case Study A 70-year-old female with a history of hypertension, hyperlipidemia, paroxysmal atrial fibrillation (AFib), and complete heart block with a dual chamber permanent pacemaker implanted 10 years prior presented to the cardiology clinic with exertional dyspnea and fatigue for…