Adenofibroma

Introduction

• Description: An adenofibroma is an epithelial tumor that consists of glandular elements and large amounts of stromal (fibrous) elements. Adenofibromas are most commonly found as ovarian masses. They may also occur in the cervix or uterine body. Adenofibromas are closely related to cystadenofibromas, which have cystic areas but still contain more than 25% fibrous connective tissue.

• Prevalence: Uncommon.

• Predominant Age: Perimenopausal and postmenopausal.

• Genetics: No genetic pattern.

Etiology and Pathogenesis

• Causes: Unknown.

• Risk Factors: None known.

Signs and Symptoms

• Asymptomatic (often an incidental finding at oophorectomy)

• Adnexal mass (adenofibromas are bilateral in 25% of cases)

• Fibrous cervical or endometrial polyp

• Acute abdominal pain if torsion occurs (rare)

Diagnostic Approach