Pramipexole

General information

Pramipexole is a non-ergot dopamine agonist similar to bromocriptine, used in the management of Parkinson’s disease as an adjunct to levodopa.

In a systematic review of randomized controlled trials of pramipexole and ropinirole, dizziness, nausea, hypotension, hallucinations, and somnolence were common adverse effects [ ]. In 306 patients adverse events secondary to pramipexole that occurred in over 10% included dyskinesias, asymptomatic orthostatic hypotension, dizziness, insomnia, and hallucinations [ ].

Organs and systems